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ProteomicsProteomic Analysis of Myotube-Secreted Exosomes of Amyotrophic Lateral Sclerosis (ALS) and Healthy subjects
In order to investigate a potential role of muscle exosomes in the pathology of Amyotrophic Lateral Sclerosis (ALS), we undertook a proteomic study of the content of exosomes secreted by myotubes of ALS and Healthy subjects.
ORGANISM(S): Homo sapiens (Human) 
2021-03-25 | PXD015736 | Pride
Muscle Exosome Myotube Motor neuron disease Als Amyotrophic lateral sclerosis 
TranscriptomicsAnalysis of gene expression in hTERT/cdk4 immortalized human myoblasts compared to their primary populations in both undifferentiatied (myoblast) and differentiated (myotube) states
hTERT/cdk4 immortalized myogenic human cell lines represent an important tool for skeletal muscle research, being used as therapeutically-pertinent models of various neuromuscular disorders and in numerous fundamental studies of muscle cell function. However, the cell cycle is linked to other cellul...
ORGANISM(S): Homo sapiens 
2016-03-16 | E-GEOD-79263 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis of aging muscle progenitors
Genome wide DNA methylation profiling of muscle cells extracted from healthy donors at different ages. The Illumina Infinium Human Methylation 450 BeadChip was used to obtain DNA methylation profiles across > 485,000 methylation sites. The muscle cells were extracted from young adults (18-40 years ...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-53302 | biostudies-arrayexpress
UnknownImpact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Not available
S-EPMC11443006 | biostudies-literature
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