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Personalized medicine aims to tailor healthcare to individual characteristics, relying on precise biological data and patient monitoring. Metabolomics and lipidomics play a key role in this approach, providing real-time insights into metabolic states and enabling accurate diagnosis and treatment ...

2026-02-25 | MTBLS13382 | MetaboLights
In response to biotic stress, plants produce suites of highly modified fatty acids that bear unusual chemical functionalities. Despite their chemical complexity and proposed roles in pathogen defense, little is known about the biosynthesis of decorated fatty acids in plants. Falcarindiol is a protot...
2022-01-17 | MTBLS1039 | MetaboLights
Human rhinoviruses (HRV) are common cold viruses associated with exacerbations of lower airways diseases. Although viral induced epithelial damage mediates inflammation, the molecular mechanisms responsible for airway epithelial damage and dysfunction remain undefined. Using experimental HRV infecti...
ORGANISM(S): Viruses Homo sapiens (Human) 
2021-04-30 | PXD024591 | Pride
Calpain-5/CAPN5 is a calcium-activated, non-lysosomal cysteine (thiol) protease. The substrate spectrum repertoire of CAPN5 is not known. Calpains catalyze limited proteolysis of their substrates, generating novel neo protein N-termini that correspond to internal residues of their nascent substrate ...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD064313 | Pride
Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play key roles in heart physiology, and this approach could pose a potential liability to cardiovascular health. Herein, using integr...
2022-09-20 | MTBLS795 | MetaboLights
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