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ProteomicsGCN5 interactome in U87MG Control, IR and doxorubicin treated conditions
GCN5 interactome in U87MG Control, IR and doxorubicin treated conditions
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD050400 | Pride
Gcn5 Irradiation Doxorubicin U87mg 
UnknownPARylation of GCN5 by PARP1 mediates its recruitment to DSBs and facilitates both HR and NHEJ Repair.
Not available
S-EPMC11544116 | biostudies-literature
UnknownRaman spectroscopy-based detection of RNA viruses in saliva: A preliminary report.
Not available
S-EPMC7361326 | biostudies-literature
UnknownInhibition of SETMAR-H3K36me2-NHEJ repair axis in residual disease cells prevents glioblastoma recurrence.
Not available
S-EPMC7746947 | biostudies-literature
UnknownA one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2.
Not available
S-EPMC7341355 | biostudies-literature
UnknownUnique spectral markers discern recurrent Glioblastoma cells from heterogeneous parent population.
Not available
S-EPMC4879554 | biostudies-literature
TranscriptomicsRNA-seq of U87MG and patient sample 2 (PS2) at different time points post-radiation treatment
Glioblastoma (GBM) is a malignant grade IV brain tumor, and despite the multimodal therapeutic approaches, which include surgery and chemo-radiotherapy, recurrence is inevitable, arising from therapy-resistant residual cells. To study the residual population's survival mechanism(s), we established a...
ORGANISM(S): Homo sapiens 
2025-08-15 | E-MTAB-14162 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of human AML cell line, HL-60 and its mitoxantrone resistant subline HL60/MX2
Alteration in metabolic repertoire is commonly associated with resistance phenotype. Although it’s a common phenotype, not much efforts have been undertaken to design effective strategies to target the metabolic drift in such cancerous cells and especially with drug resistant properties. In our stud...
ORGANISM(S): Homo sapiens 
2021-01-01 | E-MTAB-8981 | biostudies-arrayexpress
TranscriptomicsRNA-seq of in vitro radio-resistant human GBM cell line (LN229) and patient-derived culture (PS1) post YBX3 knockdown
Glioblastoma (GBM)is the most aggressive brain tumor with poor overall survival due to high recurrence rate. The recurrent GBM tumors are highly aggressive and resistant to therapy. In the current study, we explored the potential role of Y-box binding protein 3 (YBX3) in glioblastoma aggressiveness....
ORGANISM(S): Homo sapiens 
2025-12-21 | E-MTAB-14224 | biostudies-arrayexpress
TranscriptomicsRNA-seq for siPRKDC and siControl in human HL-60/MX2 mitoxantrone resistant derivative of the HL-60 cell line
Anthracyclines, topoisomerase 2 enzyme poison that results in DNA damage, are currently used in acute myeloid leukemia (AML) treatment. Identifying the mechanisms underlying drug resistance remains an important question. Here, using a mitoxantrone-resistant cell line (HL-60/MX2), we found upregulati...
ORGANISM(S): Homo sapiens 
2025-12-31 | E-MTAB-13769 | biostudies-arrayexpress
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