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ProteomicsAnalysis of DVL3 polyglutamylation using Q-TOF
Polyglutamylation is a reversible post-translational modification initially discovered on tubulin. In eukaryotes, polyglutamylation is catalyzed by enzymes from the tubulin tyrosine ligase-like (TTLL) family, which show substrate and reaction specificities that are so far mostly explored on tubulin....
ORGANISM(S): Homo sapiens (Human) 
2024-09-30 | PXD034237 | Pride
Ttll11 Wnt signaling Lc-ms Polyglutamylation Dvl3 Interactome 
GenomicsIdentification of novel DVL3 cancer-associated target genes [RNA-seq]
Identification of novel DVL3 cancer-associated target genes [RNA-seq]
PRJNA697868 | ENA
ProteomicsChange of DVL3 interacting partners upon its polyglutamylation
Polyglutamylation is a reversible post-translational modification initially discovered on tubulin. In eukaryotes, polyglutamylation is catalyzed by enzymes from the tubulin tyrosine ligase-like (TTLL) family, which show substrate and reaction specificities that are so far mostly explored on tubulin....
ORGANISM(S): Homo sapiens (Human) 
2024-09-30 | PXD033548 | Pride
Ttll11 Wnt signaling Lc-ms Polyglutamylation Dvl3 Interactome 
ProteomicsComparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.
Background: Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation generates complex barcodes underlying diverse DVL3 functions. ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD015963 | Pride
Dishevelled/dvl3/phosphorylation/kinase/mass spectrometry/ck1/ttbk2/nek2/wnt 
GenomicsIdentification of novel DVL3 cancer-associated target genes [ChIP-seq]
We report novel target genes of DVL3 in two breast cancer cell lines
ORGANISM(S): Homo sapiens 
2021-04-16 | GSE165774 | GEO
UnknownDVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts.
Not available
S-EPMC9120025 | biostudies-literature
UnknownGenetic Variants in DVL3 are Associated With Root Maldevelopment, Tooth Agenesis, Mesiodens, and Oral Exostoses.
Not available
S-EPMC12671360 | biostudies-literature
Genomics
Identification of novel DVL3 cancer-associated target genes
PRJNA693700 | ENA
UnknownDVL3 Alleles Resulting in a -1 Frameshift of the Last Exon Mediate Autosomal-Dominant Robinow Syndrome.
Not available
S-EPMC4800044 | biostudies-literature
UnknownE2F7 promotes ESCC progression and cisplatin resistance through transcriptional activation of DVL3 and the Wnt signaling pathway.
Not available
S-EPMC12771932 | biostudies-literature
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