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ProteomicsThe proteome of hand eczema assessed by tape stripping
Hand eczema (HE) is a prevalent skin disease. However, classification of HE into different subtypes remains challenging. Limited number of prior studies have employed invasive biopsy-based strategies; yet, studies of the HE proteome using non-invasive tape stripping methodology have not been reporte...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD039665 | Pride
Proteome Subtypes Atopic dermatitis Hand eczema Tape stripping 
ProteomicsComparative quantitative proteomic analysis of melanoma subtypes, nevus-associated melanoma, and corresponding nevi
A substantial part of cutaneous malignant melanomas develops from benign nevi. However, the precise molecular events driving the transformation from benign to malignant melanoma are not well understood. We used laser microdissection and mass spectrometry to analyze the proteomes of melanoma subtypes...
ORGANISM(S): Homo sapiens (Human) 
2024-01-28 | PXD044107 | Pride
Human Nevus-associated melanoma Proteomics Microdissection Skin cancer Skin Melanoma subtypes Ffpe Nevi Malignant melanoma 
ProteomicsSpatial Proteomic Profiling Reveals Increased Levels of Cholesterol Synthesis Proteins in Psoriasis Vulgaris
Background and Aims: Chronic plaque psoriasis results from genetic and environmental factors that activate inflammatory pathways involving both innate and adaptive immunity. Although the histological features are well known, protein-level changes—especially with spatial resolution—are less understoo...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD063539 | Pride
Dvp Spatial Psoriasis Immunology Inflammation 
ProteomicsSpatially and cell-type resolved quantitative proteomic atlas of healthy human skin
Human skin provides both physical integrity and immunological protection from the external environment, using functionally distinct layers, cell types and extracellular matrix. Despite its central role in human health and disease, the constituent proteins of skin have not been systematically charact...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-15 | MSV000088236 | MassIVE
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