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MetabolomicsIonic homeostasis, carbohydrate metabolism, and oxidative balance underlie wild soybean resistance to low potassium stress

The scarcity of potassium resources in farmland soils poses a major challenge to global food security. Wild soybean (Glycine soja), a valuable wild germplasm related to cultivated soybeans, is known for its high-stress resistance and adaptability. This study comprehensively compares two wild soyb...

2026-04-12 | MTBLS14256 | MetaboLights
MetabolomicsFisetin ameliorates acute colitis in mice via gut microbiota associated linoleic acid metabolism to regulate Th17/Treg balance

This study investigated the therapeutic effects of FST on colitis in mice by exploring its impact on the gut microbiota, metabolites, and immune response. The results show FST alleviated colitis in mice, including mitigated weight loss, improved colon length shortening, and reduced mRNA expressi...

2025-12-03 | MTBLS13284 | MetaboLights
ProteomicsChronic stress alters the E/I balance of pyramidal neurons in the infralimbic and Prelimbic cortices
The medial prefrontal cortex (mPFC) is a key brain region involved in controlling working memory, executive function, and self-regulatory behaviours, and its malfunction is a hallmark of several neuropsychiatric disorders such as schizophrenia, depression, and post-traumatic stress disorder. One of ...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD047291 | Pride
Infralimbic cortex Chronic stress Prelimbic cortex E/i balance 
UnknownAberrant E-I Balance and Brain Criticality in Major Depressive Disorder.
Not available
S-EPMC12633248 | biostudies-literature
UnknownForebrain E-I balance controlled in cognition through coordinated inhibition and inhibitory transcriptome mechanism.
Not available
S-EPMC10000298 | biostudies-literature
UnknownBoosting reservoir computing with brain-inspired adaptive control of E-I balance.
Not available
S-EPMC12635267 | biostudies-literature
UnknownE-I balance emerges naturally from continuous Hebbian learning in autonomous neural networks.
Not available
S-EPMC5997746 | biostudies-literature
UnknownResting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages.
Not available
S-EPMC6160226 | biostudies-literature
TranscriptomicsTranscription profiling of rat REF52 cells reveals an E2F1-dependent gene expression program that determines the balance between proliferation and cell death
E2F1 has been shown to induce both proliferation and apoptosis. We now show that PI3K/Akt signaling regulates the balance of these events by specifically blocking expression of genes in the E2F1 apoptotic program but not the proliferative program. Experiment Overall Design: 11 samples total, two rep...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9496 | biostudies-arrayexpress
UnknownGeneration of glutamatergic/GABAergic neuronal co-cultures derived from human induced pluripotent stem cells for characterizing E/I balance in vitro.
Not available
S-EPMC9898783 | biostudies-literature
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