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ProteomicsSpecific growth rate-dependent proteome resource allocation dynamics in Escherichia coli
Cells usually respond to changing growth conditions with a change in the specific growth rate (μ) and adjustment of their proteome to adapt and maintain metabolic efficiency. Description of the principles behind proteome resource allocation is thus important for understanding metabolic regulation in...
ORGANISM(S): Escherichia coli 
2015-02-27 | PXD001594 | Pride
E. coli label-free specific growth rate dependent data 
TranscriptomicsThe transcriptomic response of E. coli to triclosan exposure
The gene expression profile of E. coli K-12 MG1655 grown in minimal medium treated with 0.12 mg/L of the biocide triclosan has been analysed using whole genome oligonucleotide microarrays. "Control" RNA was isolated from three independently grown 50ml MOPS minimal media cultures of E. coli K-12 MG16...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-GEOD-15059 | biostudies-arrayexpress
TranscriptomicsThe YbjN regulon in Escherichia coli
YbjN, an enterobacteria-specific protein, is a multicopy suppressor of ts9 temperature sensitivity in Escherichia coli. Microarray study revealed that the expression level of ybjN was inversely correlated with the expression of flagellar, fimbrial and acid resistance genes. Over-expression of ybjN ...
ORGANISM(S): Escherichia coli 
2011-10-14 | E-GEOD-28630 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli planktonic samples exposed to cis-1,2-dichloroethylene (cis-DCE)
Metabolically-engineered Escherichia coli has been used previously to degrade the ubiquitous pollutant cis-1,2-dichloroethylene (cis-DCE), and the impact of the metabolic engineering was assessed by investigating the changes in the proteome. Here, genome-wide transcriptome analysis was performed to...
ORGANISM(S): Escherichia coli 
2009-11-27 | E-GEOD-13698 | biostudies-arrayexpress
ProteomicsComprehensive analysis of vanillin toxicity in Escherichia coli identifies targets for engineering improved biovanillin production
One of the key issues affecting yields of biovanillin in cell factories such as Escherichia coli is product toxicity, the mechanisms of which are poorly understood. To identify targets for engineering improved strains, we have studied mechanisms of vanillin toxicity in E. coli using a two-pronged ap...
ORGANISM(S): Escherichia coli 
2019-05-29 | PXD009242 | Pride
Escherichia coli Stress response Aldehyde Citrate synthase Copper 
ProteomicsPhase-Specific Antibiotic Resistance Mechanisms in an Escherichia coli B Strain
In this study, we used liquid chromatography–tandem mass spectrometry to quantify protein abundance in the exponential and stationary phases of BLR (DE3) cells, an Escherichia coli B strain. Our findings are consistent with previous studies, which showed that metabolic processes such as translation ...
ORGANISM(S): Escherichia coli Bacteria 
2026-09-03 | PXD065007 | Pride
Stationary and exponetial phases. antibiotic resistance E. coli 
TranscriptomicsTranscription profiling of E. coli NMB0419 mutants to investigate the role of this tetratricopeptide-repeats-encoding gene in bacterial adherence to human epithelial cells
The gene NMB0419 of Neisseria meningitidis strain MC58 encodes a putative tetratricopeptide repeats (TPR) containing protein, which was implicated in respiratory epithelial invasion. We have accordingly sought a role for NMB0419 in meningococcal adherence and invasion of human epithelial cells using...
ORGANISM(S): Escherichia coli 
2010-11-27 | E-MEXP-2485 | biostudies-arrayexpress
TranscriptomicsChIP-on-chip of OmpR binding in Salmonella enterica serovar Typhimurium strain SL1344 and E.scherichia coli strain CSH50 at pH 7 and pH 4.5 including analysis of OmpR binding in SL1344 in the absence and presence of novobiocin (25 M-NM-
OmpR is a DNA binding protein belonging to the OmpR/EnvZ two component system. This system is known to sense changes in osmolarity in Escherichia coli. Recently, OmpR in Salmonella enterica serovar Typhimurium was found to be activated by acidic pH and DNA relaxation. In this study, ChIP-on-chip wa...
ORGANISM(S): Escherichia coli K-12 
2014-03-27 | E-GEOD-49914 | biostudies-arrayexpress
ProteomicsThe SecYEG interactome of E. coli: non-competitive binding of PpiD and YidC to the SecYEG translocon
The SecYEG translocon constitutes the major protein transporting channel in bacteria and transports an enormous variety of different secretory and inner membrane proteins. The minimal core of the SecYEG translocon consists of the three inner membrane proteins SecY, SecE and SecG, which together with...
ORGANISM(S): Escherichia coli 
2019-11-07 | PXD015974 | Pride
Yidc Ppid Label-free proteomics Secyeg translocon Protein cross-linking 
ProteomicsEffects of the antibacterial compund Allicin from garlic on Escherichia coli
Allicin (diallyl thiosulfinate) from garlic is a highly potent natural antimicrobial substance. It inhibits growth of a variety of microorganisms, among them antibiotic resistant strains. Here, we show that upon exposure to allicin, growth of Escherichia coli is strongly inhibited. Growth inhibition...
ORGANISM(S): Escherichia coli 
2016-05-02 | PXD003063 | Pride
Escherichia coli Allicin Thiol S-allylmercapto 
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