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ProteomicsAn Undesirable Side Effect of EDC-catalyzed Carboxyl Labeling Approach
Carbodiimide catalyzed carboxyl and amine conjugation (amidation) has been widely used to protect carboxyl groups. N-(3-dimethylaminopropyl)-N’-ethylcarbodiimide (EDC) is the most commonly used carbodiimide reagent in protein chemis-try due to its high efficiency and high solubility in aqueous media...
ORGANISM(S): Homo sapiens (Human) 
2020-12-10 | PXD020042 | Pride
Tyrosine Carboxyl protection C-tails Edc 
MetabolomicsMicrobial and metabolic variations mediate the influence of childhood and adolescent EDC and trace element exposure on breast density.
Not available
ORGANISM(S): Homo sapiens 
ST001385 | MetabolomicsWorkbench
GenomicsEDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization
EDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization
PRJNA1140226 | ENA
GenomicsVibrio cholerae O1 str. EDC-022
Vibrio cholerae O1 str. EDC-022 Genome sequencing and assembly
PRJNA76217 | ENA
GenomicsVibrio cholerae O1 str. EDC-020
Vibrio cholerae O1 str. EDC-020 Genome sequencing and assembly
PRJNA76215 | ENA
ProteomicsInvestigating the monomer-dimer transition of PKD1 kinase domain with EDC crosslinking
The project aim was to generate experimental constraints for the in silico modeling of the dimeric structure of the PKD kinase domain. And identify conformational changes upon dimerization. For this we used the heterobifunctional zero length crosslinker EDC to identify salt bridges within the protei...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031997 | Pride
Protein kinase d Kinase domain dimer Activation loop ordering 
GenomicsVibrio cholerae strain:EDC-690
Vibrio cholerae strain:EDC-690 Genome sequencing and assembly
PRJNA598238 | ENA
ProteomicsEDC exposure during SC-islet differentiation
We aimed to asses how EDC exposure in combination with a genetic predisposition for diabetes could impact pancreatic endocrine cell development. For this, we used a protocol to generate Stem-cell islets (SC-islets) from induced pluripotent stem cells (iPSCs) following a 7 satege protocol. For 2 week...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD065436 | Pride
Sc-islets Ipscs Edc 
TranscriptomicsEDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization
Animal development is dictated by the selective and timely decay of mRNAs in developmental transitions, but the impact of mRNA decapping scaffold proteins in development is unknown. This study unveils the roles and interactions of the DCAP-2 decapping scaffolds EDC-3 and EDC-4 in the embryonic devel...
ORGANISM(S): Caenorhabditis elegans 
2024-09-23 | GSE273136 | GEO
GenomicsRna_seq analysis of muscle in click and EDC treated mouse
Rna_seq analysis of muscle in click and EDC treated mouse
PRJNA1054043 | ENA
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