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GenomicsHippuric Acid Suppresses Triple-Negative Breast Cancer via the EGFL8-Notch Signaling Axis
Hippuric Acid Suppresses Triple-Negative Breast Cancer via the EGFL8-Notch Signaling Axis
PRJNA1476123 | ENA
UnknownDown-regulation of EGFL8 regulates migration, invasion and apoptosis of hepatocellular carcinoma through activating Notch signaling pathway.
Not available
S-EPMC8207656 | biostudies-literature
TranscriptomicsHippuric Acid Suppresses Triple-Negative Breast Cancer via the EGFL8-Notch Signaling Axis
Triple-negative breast cancer (TNBC) remains a highly aggressive malignancy with limited therapeutic options due to the absence of well-defined molecular targets. Diet-induced obesity (DIO) promotes TNBC progression by reshaping systemic metabolism and inflammatory responses; however, the key circul...
ORGANISM(S): Mus musculus 
2026-06-08 | GSE334662 | GEO
ProteomicsSchwann cell plasticity regulates neuroblastic tumor cell differentiation - phosphoproteomics
The remarkable plasticity of Schwann cells (SCs) is essential for nerve regeneration but also contributes to neuropathies and cancer progression. It has not yet been investigated whether the adaptive potential of SCs is manifested in stromal, tumor associated SCs characteristically found within a be...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD022217 | Pride
Neuroblastoma Plasticity Ganglioneuroma Schwann cell Egfl8 Phosphoproteomics Stroma 
UnknownWhole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
Not available
S-EPMC8557338 | biostudies-literature
ProteomicsSchwann cell plasticity regulates neuroblastic tumor cell differentiation
The remarkable plasticity of Schwann cells (SCs) is essential for nerve regeneration but also contributes to neuropathies and cancer progression. It has not yet been investigated whether the adaptive potential of SCs is manifested in stromal, tumor associated SCs characteristically found within a be...
ORGANISM(S): Homo sapiens (Human) 
2021-01-13 | PXD018267 | Pride
Neuroblastoma Plasticity Ganglioneuroma Schwann cell Egfl8 Stroma 
TranscriptomicsSchwann cell plasticity regulates neuroblastic tumor cell differentiation
The remarkable plasticity of Schwann cells (SCs) is essential for nerve regeneration but also contributes to neuropathies and cancer progression. It has not yet been investigated whether the adaptive potential of SCs is manifested in stromal, tumor associated SCs characteristically found within a be...
ORGANISM(S): Homo sapiens 
2020-12-23 | GSE147635 | GEO
UnknownIdentification of genes with consistent methylation levels across different human tissues.
Not available
S-EPMC3950633 | biostudies-literature
UnknownEgfl7, a novel epidermal growth factor-domain gene expressed in endothelial cells.
Not available
S-EPMC1458501 | biostudies-literature
UnknownBrain Region-Specific Accumulation of Amyloidosis-Associated Proteins in Postmortem Brain Tissues of Alzheimer's Disease Patients.
Not available
S-EPMC12559104 | biostudies-literature
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