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UnknownTransformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.
Not available
S-EPMC3656605 | biostudies-literature
UnknownSelective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.
Not available
S-EPMC6666414 | biostudies-literature
TranscriptomicsEffect of EglN1 knockdown on smooth muscle expression
Ischemic preconditioning is the phenomenon whereby brief periods of sublethal ischemia protect against a subsequent, more prolonged, ischemic insult. In remote ischemic preconditioning (RIPC), ischemia to one organ protects other organs at a distance. We developed mouse models to ask if inhibition o...
ORGANISM(S): Mus musculus 
2016-02-11 | E-GEOD-77789 | biostudies-arrayexpress
ProteomicsHCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication
Human cytomegalovirus (HCMV) is a leading cause of congenital infection and morbidity in immunosuppressed populations. Like all viruses, HCMV is an obligate intracellular parasite that extensively remodels host cellular metabolism to support its replication, yet the precise underlying mechanisms and...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD074057 | Pride
Mrc5 Hcmv Egln1 Egln Adaptaquin Lc-ms/ms 
UnknownA yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.
Not available
S-EPMC2346465 | biostudies-literature
UnknownControl of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.
Not available
S-EPMC2788761 | biostudies-literature
UnknownEvolution of Key Oxygen-Sensing Genes Is Associated with Hypoxia Tolerance in Fishes.
Not available
S-EPMC11370800 | biostudies-literature
UnknownRegulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element.
Not available
S-EPMC1135001 | biostudies-literature
UnknownIdentification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains.
Not available
S-EPMC2267344 | biostudies-literature
UnknownProlonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Not available
S-EPMC10617019 | biostudies-literature
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