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ProteomicsReduced thrombogenicity of surface-treated Nitinol implants steered by altered protein adsorption
Blood-contacting medical implants made of Nitinol and other titanium alloys, such as neurovascular flow diverters and peripheral stents, have the disadvantage of being highly thrombogenic. This makes the use of systemic (dual) anti platelet / anticoagulant therapies inevitable with related risks of ...
ORGANISM(S): Homo sapiens (Human) 
2022-01-13 | PXD024284 | Pride
Proteomics Antithrombogenic treatment Cardiovascular devices Intrinsic coagulation pathway Platelet adhesion Hemocompatibility 
ProteomicsA multidimensional proteomic strategy for the characterization of the human amnion proteome
The loss of fetal membrane (FM) integrity and function in early pregnancy can have devastating consequences for the fetus and the newborn. However, the current fragmentary knowledge of FM biology has largely hampered the development of preventive FM sealing and healing strategies. Here, by an optimi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD019410 | Pride
Fetal membranes Proteomics Amnion Human proteome Extracellular matrix 
UnknownSingle cell-laden protease-sensitive microniches for long-term culture in 3D.
Not available
S-EPMC5481164 | biostudies-literature
ProteomicsProteomic Comparisoadsfasn of Intact and Fetoscopy-Induced Fetal Membrane Sites
Iatrogenic preterm premature rupture of fetal membranes (iPPROM) following fetoscopic interventions remains a major barrier to the advancement of fetal therapies. The mechanisms underlying iPPROM are poorly understood, but the inability of fetal membrane (FM) defects to heal spontaneously likely pla...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD067401 | Pride
Fetal membrane Ttts Human Ipprom 
UnknownIn Vitro and Ectopic In Vivo Studies toward the Utilization of Rapidly Isolated Human Nasal Chondrocytes for Single-Stage Arthroscopic Cartilage Regeneration Therapy.
Not available
S-EPMC9267018 | biostudies-literature
ProteomicsIntegrative analysis of mesenchymal stromal cell conversion by breast cancer secretomes in blank slate 3D microenvironments
The ability of primary tumour cells to invade and metastasise is responsible for over 90% of cancer patient deaths. During tumour growth and progression, cancer cells secrete factors that recruit and reprogram otherwise healthy cells to facilitate the formation of a favourable tumour microenvironmen...
ORGANISM(S): Homo sapiens (Human) 
2019-05-27 | PXD010467 | Pride
Lc-msms Secretome 
UnknownMesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments.
Not available
S-EPMC6549139 | biostudies-literature
UnknownAn Organ-on-Chip Platform for Strain-Controlled, Tissue-Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis.
Not available
S-EPMC12417778 | biostudies-literature
UnknownA Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues.
Not available
S-EPMC7116179 | biostudies-literature
UnknownSmart Hydrogels for the Augmentation of Bone Regeneration by Endogenous Mesenchymal Progenitor Cell Recruitment.
Not available
S-EPMC7141038 | biostudies-literature
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