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Amniotic fluid volume (AFV) is determined primarily by the rate of intramembranous (IM) transport of AF cross the amnion. Intramembranous transport is characterized as vesicular endocytotic and transcytotic processes regulated by fetal urine-derived stimulators and AF inhibitors. Our objectives were...
ORGANISM(S): Ovis aries 
2021-07-21 | PXD013135 | Pride
The loss of fetal membrane (FM) integrity and function in early pregnancy can have devastating consequences for the fetus and the newborn. However, the current fragmentary knowledge of FM biology has largely hampered the development of preventive FM sealing and healing strategies. Here, by an optimi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD019410 | Pride
Identify differentially expressed genes between the different anatomical regions of the human amnion tissue (placental amnion, reflected amnion, and umbilical amnion).
ORGANISM(S): Homo sapiens 
We investigated a potential role for SP-A in human pregnancy and parturition by examining SP-A expression patterns in amniotic fluid and the amnion
ORGANISM(S): Homo sapiens 
In this project, for the first time, the Extracellular Matrix protein compositions of porcine cornea and human amnion (amniotic membrane) were characterized using LC/MS-MS based on an already developed protocol, "Matrisome Project".
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2021-05-21 | PXD020606 | Pride
Analysis of cultured human amnion mesenchymal cells treated with synthetic glucocorticoid dexamethasone for 48 hours. Results provide insight into the molecular response of the human amnion to glucocorticoids.
ORGANISM(S): Homo sapiens 
Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of w...
ORGANISM(S): Homo sapiens 
The protein content of amnion is thought to be the primary contributor to its efficacy as a biological dressing for wounds. Protein elution into antibiotic processing media has been reported, but the effect of antiseptic-based processing methods is unknown. Here, proteomic analyses of equine amnion ...
ORGANISM(S): Cellular Organisms 
Profiling the transient gastrulation inducing property of amnion-like cells.
Marmoset epiblast and amnion spheroids as models for postimplantation lineage specification
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