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TranscriptomicsIntegrated analysis of genome-wide copy number and matched expression data reveals novel genes in esophageal adenocarcinoma
The incidence of esophageal and junctional adenocarcinoma has increased 6-fold in the west in the last 30 years and 5 year survival remains <14%. We aimed to characterize genome-wide aberrations in esophageal adenocarcinoma to further understand disease pathogenesis and ultimately identify groups wi...
ORGANISM(S): Homo sapiens 
2011-05-09 | E-GEOD-25201 | biostudies-arrayexpress
TranscriptomicsSmall bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers
Purpose: Small bowel adenocarcinoma (SBA) is a rare cancer and consequently the number of clinical trials has been very limited due to the small numbers of patients. Chemotherapy regimens are currently rather arbitrarily chosen between either a colorectal (CRC) or a gastric cancer (GC) regimen. Chr...
ORGANISM(S): Homo sapiens 
2011-06-13 | E-GEOD-23418 | biostudies-arrayexpress
GenomicsTumor-specific expression of let-7i and miR-192 is associated with resistance to cisplatin-based chemoradiotherapy in patients with larynx and hypopharynx cancer
Background: The majority of patients with locally advanced larynx or hypopharynx squamous cell carcinoma are treated with organ preserving chemoradiotherapy (CRT). Clinical outcome following CRT varies greatly. We hypothesized tumor microRNA (miRNA) expression is predictive for outcome following CRT...
EGAS00001004001 | EGA
UnknownEngineering large-scale chromosomal deletions by CRISPR-Cas9.
Not available
S-EPMC8643637 | biostudies-literature
TranscriptomicsUnderstanding Vitamin D resistance using Nonsense Mediated Decay arrays
Vitamin D is the strongest known natural anti-proliferative. A large number of studies in a wide spectrum of cancers, including epidemiological, in vitro and animal models, demonstrate that the active form of Vitamin D has anti-cancer benefits, affecting both progression and metastasis. Alike the ro...
ORGANISM(S): Homo sapiens 
2008-06-01 | E-GEOD-9959 | biostudies-arrayexpress
TranscriptomicsUnderstanding Vitamin D resistance using expression microarrays
Vitamin D is the strongest known natural anti-proliferative. A large number of studies in a wide spectrum of cancers, including epidemiological, in vitro and animal models, demonstrate that the active form of Vitamin D has anti-cancer benefits, affecting both progression and metastasis. Alike the ro...
ORGANISM(S): Homo sapiens 
2008-05-31 | E-GEOD-9867 | biostudies-arrayexpress
TranscriptomicsUnderstanding Vitamin D resistance using array comparative genomic hybridization
Vitamin D is the strongest known natural anti-proliferative. A large number of studies in a wide spectrum of cancers, including epidemiological, in vitro and animal models, demonstrate that the active form of Vitamin D has anti-cancer benefits, affecting both progression and metastasis. Alike the ro...
ORGANISM(S): Homo sapiens 
2008-05-31 | E-GEOD-9887 | biostudies-arrayexpress
Genomicsena-DATASET-VUMC-CCA-05-12-2021-12:21:28:910-387 - samples
small RNA next generation sequencing in head and neck cancer
EGAD00001008402 | EGA
UnknownCirculating Tumor DNA as a Preoperative Marker of Recurrence in Patients with Peritoneal Metastases of Colorectal Cancer: A Clinical Feasibility Study.
Not available
S-EPMC7357031 | biostudies-literature
TranscriptomicsTranscription profiling of human primary lung adenocarcinomas
We have investigated whether the early dissemination of tumor cells into bone marrow is associated with a specific molecular pattern in primary lung cancer Experiment Overall Design: two groups of primary lung adenocarcinomas were compared differentiating in the metastatic potential
ORGANISM(S): Homo sapiens 
2009-03-14 | E-GEOD-10799 | biostudies-arrayexpress
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