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ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Fecal Transplant
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003170 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases: Clindamycin
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003168 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Control for Cln, C. diff, Fecal Transplant
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003167 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:C. difficile infection
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003169 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases: DSS
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003171 | Pride
Mouse Fecal transplant Gut microbiome Antibiotic C difficile 
ProteomicsHost-microbiota interactions in the pathogenesis of antibiotic-associated diseases:Streptomycin plus Salmonella
Improved understanding of the interplay between host and microbes stands to illuminate new avenues for disease diagnosis, treatment and prevention. Here, we provide a high-resolution view of the dynamics between host and gut microbiota during antibiotic induced intestinal microbiota depletion, oppor...
ORGANISM(S): Mus musculus (Mouse) 
2016-02-04 | PXD003152 | Pride
Inflammation Gut Antibiotic Mouse Pathogen Microbiome 
ProteomicsA375 melanoma cell line, Expanded database search comparisons
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Mass spectrometry is well suited to PTM identification, but proteome-scale analyses are biased towards PTMs with existing enrichment methods. To measure the full landscape of PTM regulation...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD005912 | Pride
Taggraph opensearch a375 melanoma 
ProteomicsThe effect of microbial colonization on the host proteome varies by gastrointestinal location
Endogenous intestinal microbiota have wide-ranging and largely uncharacterized effects on host physiology. Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to define the mouse intestinal proteome in the stomach, jejunum, ileum, cecum, and proximal colon under three ...
ORGANISM(S): Mus musculus (Mouse) 
2015-11-25 | PXD002838 | Pride
Mouse gut microbiome host-centric proteomics 
ProteomicsRe-analysis of Hela phosphoproteome (PXD000612) with TagGraph
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Although mass spectrometry is suited to PTM identification, it has historically been biased towards a few with established enrichment procedures. To measure all possible PTMs across diverse...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD008899 | Pride
Taggraph Ptm Hela Posphorylation 
ProteomicsTagGraph re-analysis of a lung proteome (Peptide Atlas PAe001771), which was a component of the Wilhelm et al human proteome map
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Although mass spectrometry is suited to PTM identification, it has historically been biased towards a few with established enrichment procedures. To measure all possible PTMs across diverse...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD008902 | Pride
Taggraph Lung Ptm 
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