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ProteomicsRe-analysis of Hela phosphoproteome (PXD000612) with TagGraph
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Although mass spectrometry is suited to PTM identification, it has historically been biased towards a few with established enrichment procedures. To measure all possible PTMs across diverse...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD008899 | Pride
Taggraph Ptm Hela Posphorylation 
ProteomicsTagGraph re-analysis of a lung proteome (Peptide Atlas PAe001771), which was a component of the Wilhelm et al human proteome map
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Although mass spectrometry is suited to PTM identification, it has historically been biased towards a few with established enrichment procedures. To measure all possible PTMs across diverse...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD008902 | Pride
Taggraph Lung Ptm 
ProteomicsA375 melanoma cell line, Expanded database search comparisons
Thousands of protein post-translational modifications (PTMs) dynamically impact nearly all cellular functions. Mass spectrometry is well suited to PTM identification, but proteome-scale analyses are biased towards PTMs with existing enrichment methods. To measure the full landscape of PTM regulation...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD005912 | Pride
Taggraph opensearch a375 melanoma 
UnknownTagGraph reveals vast protein modification landscapes from large tandem mass spectrometry datasets.
Not available
S-EPMC6447449 | biostudies-literature
ProteomicsA systematic evaluation of common yeast whole cell lysate proteomics sample preparation protocols
The continuing ‘desire’ in obtaining more quantitative and detailed information from cellular proteomics experiments in regards to proteome coverage and protein modifications asks for a systematic investigation of the protein extraction and digestion protocols, in particular when working with unicel...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-03-31 | PXD026806 | Pride
Yeast Shotgun proteomics Ms artefacts Modifications Sample preparation 
UnknownIdentification of modified peptides using localization-aware open search.
Not available
S-EPMC7426425 | biostudies-literature
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