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Virological research has traditionally focused on individual viruses or viral families. Advances in DNA synthesis now allow large-scale construction of individual gene products, enabling systematic exploration of the virome. Here, we developed a barcoded library of ~12,000 viral open reading frames ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD077768 | Pride
TMT-MS of total proteomes of TXNL1-KO HEK293T cells or TXNL1-KO cells complemented with wild type and proteasome binding deficient mutant (D162R, R234D) version of TXNL1 treated with or without 100 µM arsenite for 3 hours.
ORGANISM(S): Homo sapiens (Human) 
2025-05-28 | PXD052933 | Pride
Cell fate transitions involve rapid changes of gene expression patterns and global chromatin remodeling, yet the underlying regulatory pathways remain incompletely understood. Here, we used transcription-factor induced reprogramming of somatic cells into pluripotent cells to screen for novel regulat...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-08 | PXD008078 | Pride
The first bona fide PTP proto-oncogene was the Src-homology 2 domain-containing phosphatase SHP2 (encoded by PTPN11), an ubiquitously expressed PTP that transduces mitogenic, pro-survival, cell fate and/or pro-migratory signals from numerous growth factor-, cytokine- and extracellular matrix recepto...
ORGANISM(S): Homo sapiens 
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