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TranscriptomicsCellular senescence reprograms human NK cells to promote vascular remodeling
Natural killer (NK) cells are lymphocytes that participate in immune responses through their cytotoxic activity and secretion of cytokines and chemokines. They can be activated by interaction with ligands on target cells or by soluble mediators such as cytokines. In addition, soluble HLA-G, a major ...
ORGANISM(S): Homo sapiens 
2012-12-03 | E-GEOD-35330 | biostudies-arrayexpress
UnknownATP-dependent membrane remodeling links EHD1 functions to endocytic recycling.
Not available
S-EPMC6281616 | biostudies-literature
ProteomicsPten regulates endocytic trafficking of cell adhesion and signaling molecules to pattern the retina
The retina is an exquisitely patterned tissue, with neuronal somata positioned at regular intervals to completely sample the visual field. Cholinergic amacrine cells are spectacular exemplars of precision, distributing in two radial layers and tangentially, forming regular mosaics. Here, we investig...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-09 | PXD036221 | Pride
Cholinergic amacrine cell Cell adhesion molecules Mosaicism Extracellular vesicles Retina Wnt signaling Endocytic remodeling Pten phosphatase Dscam 
UnknownEndocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling.
Not available
S-EPMC8685726 | biostudies-literature
UnknownDifferential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis.
Not available
S-EPMC3734290 | biostudies-literature
ProteomicsMacrophage PAK2 controls the SIRPα immune checkpoint via cytoskeletal dynamics and endocytic trafficking
Professional phagocytes are essential for immunomodulation, antimicrobial control, and initiation and resolution of inflammation. These cells rely on dynamic cytoskeletal rearrangements to respond to their environment. This plasticity requires a network of positive and negative regulators to control...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-31 | PXD062325 | Pride
Pak2 Endocytic trafficking. Sirpα immune checkpoint Macrophage 
ProteomicsLRP1 in Vascular Remodeling and Angiotensin Signaling
Vascular smooth muscle cells (vSMC) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor-related protein 1 (LRP1), a large endocytic and signaling receptor that recognizes numerous ligands including ApoE-rich lipopro...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD038236 | Pride
Ace/angiotensin receptors/renin angiotensin system Smooth muscle proliferation and differentiation Vascular biology Lrp1 Tgf-β Sma remodeling Ang ii Hemodynamics Remodeling Animal models of human disease Proteomics Smooth muscle cells 
UnknownSpatiotemporal dynamics of membrane remodeling and fusion proteins during endocytic transport.
Not available
S-EPMC4454181 | biostudies-literature
UnknownA systematic approach to identify recycling endocytic cargo depending on the GARP complex.
Not available
S-EPMC6374077 | biostudies-literature
UnknownThe GTPase-activating protein GRAF1 regulates the CLIC/GEEC endocytic pathway.
Not available
S-EPMC2726289 | biostudies-literature
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