Sort   by:  
 Page size 
UnknownIn Vitro and In Vivo Investigation of Potential for Complex CYP3A Interaction for PF-00251802 (Dagrocorat), a Novel Dissociated Agonist of the Glucocorticoid Receptor.
Not available
S-EPMC5900965 | biostudies-literature
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
Proteomicsyeast_cell_lysate
yeast_quality_control
ORGANISM(S): Saccharomyces Cerevisiae 
2006-12-31 | PAe000324 | PeptideAtlas
TranscriptomicsRNA-seq of the human HCC cell line PLC5 after 72 hours treatment with either MAGEA3 shRNA or Scramble control
To better understand the mechanism by which MAGEA3 contributes to HCC progression, we conducted RNA sequencing in the PLC5 HCC cell line after 72 hours of treatment with scramble or sh8375 in triplicate. RNA-sequencing was conducted on poly-A enriched RNA, 100 bp single reads using an Illumina HiSeq...
ORGANISM(S): Homo sapiens 
2021-05-19 | E-MTAB-8860 | biostudies-arrayexpress
ProteomicsIntestine proteome of Rhipicephalus microplus tick reveal key molecular features associated with resistant to ivermectin
Rhipicephalus microplus is among the critical tick parasite of cattle farming globally. However, the massive use of ivermectin last decades induced the generation of the tick-resistant population. Unfortunately, despite extensive research the mode of action of ivermectin remains unclear. Due to the...
ORGANISM(S): Rhipicephalus microplus 
2024-01-29 | PXD031231 | Pride
Lc-ms Ivermectin Sps Proteome Rhipicephalus microplus 
GenomicsComplete Genomics paired end sequencing; Ovarian cancer
We sequenced the genomes from a monozygotic twin discordant for schizophrenia and a tumor-normal pair of an ovarian cancer patient. Using whole-genome twin data to discriminate between correctly identified single nucleotide variants (SNVs) and errors a strategy for the accurate detection of SNVs was...
EGAS00001000158 | EGA
TranscriptomicsA spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche - Visium
Multiple distinct cell types of the human lung and airways have been defined by single cell RNA sequencing (scRNAseq). Here we present a multi-omics spatial lung atlas to define novel cell types which we map back into the macro- and micro-anatomical tissue context to define functional tissue microen...
ORGANISM(S): Homo sapiens 
2022-01-06 | E-MTAB-11640 | biostudies-arrayexpress
ProteomicsExercise prevents substrate overload of liver mitochondria by modification of the compensatory responses during chronic overnutrition
Exercise training is a potent treatment of NAFLD and hepatic insulin resistance. Here we provide molecular information about the hepatic mitochondrial metabolism in mice when chronic overnutrition (high-energy diet (HED) for 6 weeks) is combined with exercise training. Training reduced the hepatic t...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024308 | Pride
Exercise Mitochondria Dia Mouse Lipidomics Proteomics Lc-ms/ms 
TranscriptomicsMicroRNA Expression in Cutaneous Squamous Cell Carcinoma
Cutaneous squamous cell carcinoma (cSCC) is the second most commonly diagnosed cancer in the United States each year. Despite a generally good prognosis, metastatic cSCC results in over 3500 deaths annually. There are no specifically targeted therapies or biomarkers for metastatic cSCC. To determine...
ORGANISM(S): Homo sapiens 
2015-02-28 | E-GEOD-57768 | biostudies-arrayexpress
GenomicsDNA IP for 5hmC modified CpGs in the liver of control mice and a Tet1 -/- mouse liver [hmeDIP-seq]
Through the analysis of mouse liver tumours promoted by distinct routes (DEN exposure alone, DEN exposure plus non-genotoxic insult with phenobarbital and non-alcoholic fatty liver disease); we report that the cancer associated hyper-methylated CGI events in mice are also predicated by silent promot...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-77730 | biostudies-arrayexpress
Sort   by:  
 Page size