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TranscriptomicsGene expression in phagocytic and non-phagocytic Entamoeba histolytica populations
The ability of Entamoeba histolytica to phagocytose host cells correlates to observed virulence in vivo. To better understand the mechanism of phagocytosis we used paramagnetic beads coated with host ligand and sorted trophozoites based on phagocytic ability. Gene expression was then measured in bot...
ORGANISM(S): Entamoeba histolytica 
2012-10-16 | E-GEOD-41604 | biostudies-arrayexpress
ProteomicsComparative Proteomic Study of Entamoeba histolytica Trophozoites, Cysts, and Cyst-Like Structures
Proteomic comparison between trophozoites, cysts and cyst-like structures of Entamoeba histolytica
ORGANISM(S): Entamoeba Histolytica (ncbitaxon:5759) 
2016-04-21 | MSV000079674 | MassIVE
TranscriptomicsRole of REG 1 in Entamoeba histolytica colitis
Differential expression was used to access gene differences after Entamoeba histolytica infection. Entamoeba histolytica is an important diarrheal pathogen worldwide, and induces apoptosis of the intestinal epithelium as part of its disease process. Regenerating (REG) 1 protein is anti-apoptotic. ...
ORGANISM(S): Homo sapiens 
2011-05-24 | E-GEOD-23750 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica trophozoites in mid-logarithmic growth
Entamoeba histolytica is a protozoan parasite which causes colitis and liver abscesses. Using a genomic DNA microarray consisting of 1.6 - 2.0 kb genomic inserts we have generated a transcriptional profile of 1,971 unique parasite transcripts. The 12 arrays in this experiment set were used to esti...
ORGANISM(S): Entamoeba histolytica 
2005-07-06 | E-SMDB-3205 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica plus Caco2 cells
Entamoeba histolytica is a protozoan parasite which causes colitis and liver abscesses. Using a genomic DNA microarray consisting of 1.6 - 2.0 kb genomic inserts we have generated a transcriptional profile of 1,971 unique parasite transcripts. The arrays in this experiment set were used to examine...
ORGANISM(S): Entamoeba histolytica 
2005-07-06 | E-SMDB-3208 | biostudies-arrayexpress
GenomicsWhole genome bisulfite sequencing of Entamoeba histolytica
Up until now, the existence of Dnmt2-mediated DNA methylation has mostly been supported by focal analyses in organisms that contain Dnmt2, but no Dnmt1 or Dnmt3 DNA methyltransferase. In these organisms, several independent studies have also provided support for a biologically important function of ...
ORGANISM(S): Entamoeba histolytica 
2011-08-10 | E-GEOD-31295 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica virulent and nonvirulent entamoeba species
Entamoeba histolytica is a protozoan parasite that causes colitis and liver abscesses. Several Entamoeba species and strains with differing levels of virulence have been identified. E. histolytica HM-1:IMSS is a virulent strain, E. histolytica Rahman is a nonvirulent strain, and Entamoeba dispar is ...
ORGANISM(S): Entamoeba histolytica 
2006-01-03 | E-SMDB-3589 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Entamoeba histolytica trophozoites
This SuperSeries is composed of the following subset Series: GSE2978: Entamoeba heat shock experiments GSE2979: Entamoeba plus Caco2 cells Abstract: We have developed an Entamoeba histolytica genomic DNA microarray and used it to develop a transcriptional profile of 1,971 E. histolytica (HM-1:IMSS)...
ORGANISM(S): Entamoeba histolytica 
2006-03-07 | E-GEOD-4400 | biostudies-arrayexpress
ProteomicsCoactosin phosphorylation controls Entamoeba histolytica 1 cell membrane protusions and cell motility
Invasion of the colon wall by Entamoeba histolytica during amoebic dysentery entails migration of trophozoites through tissue layers that are rich in extracellular matrix (ECM). Transcriptional silencing of the E. histolytica matrix surface metalloprotease EhMSP-1 produces hyper-adherent, less motil...
ORGANISM(S): Entamoeba histolytica HM-1:IMSS-B Entamoeba histolytica HM-1:IMSS-A Entamoeba histolytica HM-1:IMSS Entamoeba histolytica 
2020-07-15 | PXD018276 | Pride
Lc-msms Phosphopeptides Entamoeba histolytica 
TranscriptomicsSmall RNA pyrosequencing in the protozoan parasite Entamoeba histolytica reveals strain-specific small RNAs that target virulence genes
We provided a full spectrum analysis for E. histolytica AGO2-2 associated 27nt small RNAs. Additionally, comparative analysis of small RNA populations from virulent and non-virulent amebic strains indicates that small RNA populations may regulate virulence genes. AGO2-2 bound small RNAs from E. hist...
ORGANISM(S): Entamoeba histolytica 
2013-01-24 | E-GEOD-43668 | biostudies-arrayexpress
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