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Entosis is a process that leads to the formation of cell-in-cell structures commonly found in cancers. Here, we identified entosis in hepatocellular carcinoma and the loss of Rnd3 as an efficient inducer of this mechanism. We characterized the different stages and the molecular regulators of entosis...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD043640 | Pride
Cell-in-cell-mediated entosis reveals a progressive mechanism in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy with high intratumoral heterogeneity. There is a lack of effective therapeutics for PDAC. Entosis, a form of nonapoptotic regulated cell death mediated by cell-in-cell structures (CICs), has been reported in multiple cancers. However, th...
ORGANISM(S): Homo sapiens 
2023-08-31 | GSE241563 | GEO
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