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Environmental exposure of placental explants did not change the quantity of exosomes or their characteristics. However, exosome cargo composition was changed by specific pollutant to reflect a biochemical signature suggestive of placental nuclear and cellular injury and inflammation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
Environmental enrichment has been reported to delay or restore age-related cognitive deficits, however, a mechanism to account for the cause and progression of normal cognitive decline and its preservation by environmental enrichment is lacking. Using genome-wide SAGE-Seq, we provide a global assess...
ORGANISM(S): Mus musculus 
The experiment utilized a total of 54 five-week-old Sprague-Dawley rats, each weighing approximately 100 grams. These rats were randomly divided into 9 groups, consisting of 27 female and 27 male rats. Based on the intervention dose of cadmium (Cd), the rats were further randomly assigned into 3 mai...
ORGANISM(S): Rattus Rattus 
2025-04-16 | PXD063013 |
Peptides were identified during degradation of the diatom Thalassiosira weissflogii with and without the use of the enzyme trypsin. This allows comparison of protein degradation occurring within the experiment (no trypsin added; peptides already present due to in situ degradation) and the protein s...
ORGANISM(S): environmental samples <diatoms 
2021-12-20 | PXD027843 | Pride
The effect of environmental salinity on the gill proteome was isolated in controlled mesocosm experiments. Salinity-dependent changes in the gill proteome were analyzed by LCMSMS data-independent acquisition (DIA) and Skyline. For this purpose, relative abundances of 1691 proteins representing the m...
ORGANISM(S): Gasterosteus Aculeatus 
2020-09-24 | PXD017662 | panorama
Metals at high concentrations can exert toxic effects on microorganisms. It has been widely reported that lowering environmental pH reduces effects of cadmium toxicity in bacteria. Understanding the effects of pH-mediated cadmium toxicity on bacteria would be useful for minimizing cadmium toxicity...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
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