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This study aimed to identify proteolytic fragments of gluten proteins recognized by recombinant IgG1 monoclonal antibodies generated from single IgA plasma cells of celiac disease lesions. Peptides bound by monoclonal antibodies in complex gut-enzyme digests of gluten treated with the deamidating en...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080779 | MassIVE
Here, we have determined rhGAA ADA epitopes in the plasma samples of Pompe disease patients using series of affinity purifications combined with epitope extraction and label free quantitation LC-MS methodology
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD065994 | Pride
Commensal epitopes drive differentiation of colonic Tregs
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus control. Here, we identified non-synonymous mutations in MHC-I restricted CD8+ T cell epitopes after deep sequencing of 747 SARS-CoV-2 virus isolates. Mutant peptides exhibited diminished or abrogated MHC-I binding...
This study aimed to identify proteolytic fragments of gluten proteins recognized by recombinant IgG1 monoclonal antibodies generated from single IgA plasma cells of celiac disease lesions. Peptides bound by monoclonal antibodies in complex gut-enzyme digests of gluten treated with the deamidating en...
ORGANISM(S): Homo sapiens (Human) 
2016-05-10 | PXD002678 | Pride
Listeria monocytogenes is a foodborne intracellular bacterial model pathogen. Protective immunity against Listeria depends on an effective CD8 T-cell responses, but very few T cell epitopes are known in mice as most common animal infection model for listeriosis. To identify epitopes we screened for ...
ORGANISM(S): Mus musculus (Mouse) Listeria monocytogenes 
2024-08-13 | PXD047750 | Pride
Influenza viruses (IV) infection is a public health concern worldwide. Currently, all available vaccines as well as antiviral drugs that target the virus itself are prone to resistance. Lessons learned from previous pandemic outbreaks is that people with a preexisting cellular immune response are ei...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD035241 | Pride
Sanjuan2013 - Evolution of HIV T-cell epitope, control model Control model in which the virus targets a nonimmune cell type C (e.g., hepatocytes, epithelial cells, etc.), instead of T H cells. This model is described in the article:...
2005-01-01 | MODEL1302180002 | BioModels
Improved predictions of immunogenicity reveal SARS-Cov-2 CD8 T-cell epitopes
Sanjuan2013 - Evolution of HIV T-cell epitope, immune activation model Model of cellular immune response against HIV. This model is described in the article: Immune activation promotes evolutionary conservation of T-cell epitopes ...
2005-01-01 | MODEL1302180001 | BioModels
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