Sort   by:  
 Page size 
MetabolomicsGut Microbiota–Derived Ergothioneine Alleviates Antipsychotic-Induced Synaptic and Cognitive Impairments

Background: Chronic use of antipsychotic drugs is associated with neuronal damage and cognitive impairment, potentially mediated by alterations in gut microbiota metabolites, although the specific metabolite involved remains unknown.

Objective: To identify the key metabolite responsible for...

2026-04-08 | MTBLS12751 | MetaboLights
TranscriptomicsTranscritpome analysis of Mycobacterium tuberculosis (Mtb) mutants deficient in ergothioneine, or mycothiol production
This experiment was performed to determine deferentially regulated genes in the absence of redox buffer ergothioneine (EGT), or mycothiol (MSH). We had used two Mtb mutants namely egtA:Tn and egtD:Tn which are deficient in EGT production ( Transposon Mutant of EGT biosynthesis pathway); In additi...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2016-01-27 | E-MTAB-4099 | biostudies-arrayexpress
GenomicsEfect of L-Ergothioneine treatment in kidneys of Slc7-/- cystinuria mouse model
Efect of L-Ergothioneine treatment in kidneys of Slc7-/- cystinuria mouse model
PRJNA1369584 | ENA
GenomicsTranscriptional analysis of transposon mutants disrupted in glutathione or ergothioneine biosynthesis in Burkholderia thailandensis
Transcriptional analysis of transposon mutants disrupted in glutathione or ergothioneine biosynthesis in Burkholderia thailandensis
PRJNA1005314 | ENA
TranscriptomicsTranscriptional analysis of transposon mutants disrupted in glutathione or ergothioneine biosynthesis in Burkholderia thailandensis
In this study we compare logrithmically grown Burkholderia thailadensis wildtype to a transposon mutant that is disrupted in gshA1, or gshA2, which are involved in glutathione biosynthesis or egtB, involved in ergothioneine biosynthesis using RNASeq to identify novel pathways where glutathione or er...
ORGANISM(S): Burkholderia thailandensis 
2026-07-07 | GSE240826 | GEO
TranscriptomicsEfect of L-Ergothioneine treatment in kidneys of Slc7-/- cystinuria mouse model
Cystinuria (OMIM #220100) is the most common inherited aminoaciduria and it is caused by mutations in the SLC3A1 and SLC7A9 genes, which encode the heavy and light subunits of the b0,+ amino acid transport system. Defects in renal reabsorption lead to the hyperexcretion of cystine, lysine, arginine ...
ORGANISM(S): Mus musculus 
2026-02-01 | GSE311516 | GEO
UnknownEngineering ergothioneine production in Yarrowia lipolytica.
Not available
S-EPMC9299812 | biostudies-literature
GenomicsSingle-cell transcriptomics identifies ergothioneine as a mitochondrial protector to prevent AKI-to-CKD progression
Single-cell transcriptomics identifies ergothioneine as a mitochondrial protector to prevent AKI-to-CKD progression
PRJNA1462235 | ENA
ProteomicsErgothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation
Ergothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET's effects on healthspan in aged animals, revealing extension of lifespan and enhanced mobility in Caenorhabditis elegans, accompan...
ORGANISM(S): Caenorhabditis elegans 
2025-01-21 | PXD051587 | Pride
Ergothioneine Healthspan Persulfidation Hydrogen sulfide Nad 
UnknownS-Methyl-L-Ergothioneine to L-Ergothioneine Ratio in Urine Is a Marker of Cystine Lithiasis in a Cystinuria Mouse Model.
Not available
S-EPMC8471778 | biostudies-literature
Sort   by:  
 Page size