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ProteomicsMDA-MB-231 Breast Cancer Bone Tropic vs Parental Hypoxic Secretome Analysis
The project profiled the expression patterns in hypoxia induced secretomes between MDA-MB-231 parental and MDA-MB-231 Bone Tropic (BT) breast cancer cell lines which have been previously generated by Massague and colleagues (Kang et al. Cancer Cell 2003).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080797 | MassIVE
ProteomicsProteomic characterisation of Caenorhabditis elegans larval development
The nematode Caenorhabditis elegans (C. elegans) is often used as a model organism to study cell and developmental biology. Quantitative mass spectrometry has only recently been performed in C. elegans and, so far, most studies have been done on adult worm samples. Here we use quantitative mass spec...
ORGANISM(S): Caenorhabditis elegans 
2017-12-04 | PXD006676 | Pride
Caenorhabditis elegans Lc-ms Larvae Development 
ProteomicsMDA-MB-231 Breast Cancer Bone Tropic vs Parental Hypoxic Secretome Analysis
The project profiled the expression patterns in hypoxia induced secretomes between MDA-MB-231 parental and MDA-MB-231 Bone Tropic (BT) breast cancer cell lines which have been previously generated by Massague and colleagues (Kang et al. Cancer Cell 2003).
ORGANISM(S): Homo sapiens (Human) 
2015-05-28 | PXD000397 | Pride
Lysyl oxidase  breast cancer  hypoxia  secretome  pre-metastatic niche  bone 
ProteomicsIntegrative analysis of mesenchymal stromal cell conversion by breast cancer secretomes in blank slate 3D microenvironments
The ability of primary tumour cells to invade and metastasise is responsible for over 90% of cancer patient deaths. During tumour growth and progression, cancer cells secrete factors that recruit and reprogram otherwise healthy cells to facilitate the formation of a favourable tumour microenvironmen...
ORGANISM(S): Homo sapiens (Human) 
2019-05-27 | PXD010467 | Pride
Lc-msms Secretome 
ProteomicsPhospho-networks in Ovarian Cancer Cell Lines
Cancer cells acquire pathological phenotypes through accumulation of mutations that perturb signaling processes. While thousands of mutations have been identified, mostly by genome-wide sequencing, systematic interpretation of their role in cancer and impact on cellular information processing is pre...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080700 | MassIVE
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