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During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host. Following invasion of the snail, the parasite develops from a miracidium to...
ORGANISM(S): Biomphalaria glabrata 
Haemonchus contortus has developed complexed and multifaceted mechanisms of immune evasion to enable the survival in the host. Generating excretion and secretion products (ESPs) to subvert or suppress the functions of host cytokines is a newly immune regulatory pattern found during recent years. TGF...
ORGANISM(S): Haemonchus contortus (Barber pole worm) 
2020-09-08 | PXD020699 | Pride
Schistosomiasis, caused by infection with Schistosoma trematode parasites, is one of the deadliest neglected tropical diseases in the world. The Schistosoma lifecycle involves the miracidia infection of an intermediate molluscan host, such as Biomphalaria glabrata. Dispersing B. glabrata attractant ...
ORGANISM(S): Biomphalaria glabrata Schistosoma mansoni (Blood fluke) 
2022-10-03 | PXD031989 | Pride
Entomopathogenic nematodes (EPNs) are gaining significant popularity as biocontrol agents due to their ability to rapidly kill insect hosts. These nematodes produce bioactive molecules known as excreted/secreted products (ESPs) that help them overcome host immune defenses. Understanding the mechanis...
ORGANISM(S): Heterorhabditis bacteriophora 
2025-02-10 | PXD056325 | Pride
The aims of this study were to study ESPs to improve understanding of parasite-host interactions and to support the discovery of novel diagnostic or therapeutic targets. We used tandem mass-spectrometry to characterize the secretome of adult P. kellicotti flukes and to compare ESPs released during i...
ORGANISM(S): Paragominus Kellikotti 
2022-06-02 | MSV000089589 | MassIVE
A total of 1,301 differentially expressed genes were identified: 521 upregulated and 780 downregulated. Furthermore, p21 and PAI levels decreased, which coincided with decreases in E-cadherin and increases in fibronectin expression, in cells stimulated with Clonorchis sinensis excretory/secretory pr...
ORGANISM(S): Homo sapiens 
2019-10-14 | GSE138806 | GEO
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