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ProteomicsImmunotherapeutic antibodies derived from human tumor tertiary lymphoid structures
We report that intratumoral Tertiary Lymphoid Structures (TLS) in human ovarian cancer contain highly oligoclonal B cells that produce IgA and IgG. Using a recombinant antibody cloned from the dominant sequence of an ovarian cancer TLS, we abrogated the growth of the autologous human tumor in vivo, ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-12 | PXD036740 | Pride
Ovarian cancer Target identification Antibodies Tertiary lymphoid structures 
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