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TranscriptomicsMicroarray characterization of gene expression changes in blood during acute ethanol exposure
As part of the civil aviation safety program to define the adverse effects of ethanol on flying performance, we present results of our DNA microarray analysis of samples from a timecourse study of individuals given ethanol orally, and then evaluated by breathalyzer to monitor blood alcohol content (...
ORGANISM(S): Homo sapiens 
2013-07-25 | E-GEOD-20489 | biostudies-arrayexpress
ProteomicsProteomic profiling of ethanol tolerance in yeast
For yeast cells, tolerance to high levels of ethanol is vital both in their natural environment and in industrially relevant conditions. We recently genotyped experimentally evolved yeast strains, tolerant to high levels of ethanol. In this study, we elucidate how the genotype and phenotype are rela...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-12-03 | PXD006631 | Pride
Experimental evolution Ethanol stress Yeast 
TranscriptomicsEthanol alters microNA expression in zebrafish embryos
Prenatal exposure to ethanol leads to a myriad of developmental disorders known as fetal alcohol spectrum disorder, often characterized by growth and mental retardation, central nervous system damage and specific craniofacial dysmorphic features. Although the exact mechanisms of ethanol toxicity are...
ORGANISM(S): Danio rerio 
2012-06-17 | E-GEOD-32632 | biostudies-arrayexpress
ProteomicsDetection of Lactococcus lactis contamination in standard and ethanol-washed casein used in mouse diets for microbiome studies
Casein is a common source of dietary protein in defined diets used to investigate the effect of diet on the gut microbiota. Previously it has been shown that the metagenomes of mice fed with a diet containing casein were contaminated with DNA from the bacterium Lactococcus lactis and that washing th...
ORGANISM(S): Bos taurus (Bovine) Lactococcus lactis 
2024-12-18 | PXD040649 | Pride
Microbiome Mouse diets Casein Microbiota Ethanol wash Metaproteomics Dietary protein 
TranscriptomicsPrefrontal cortex gene expression in WSP and WSR male and female mice following chronic ethanol exposure during peak withdrawal at 8hr
While women are more vulnerable than men to many of the medical consequences of alcohol abuse, the role of sex in the response to ethanol is controversial. Neuroadaptive responses that result in the hyperexcitability associated with withdrawal from chronic ethanol likely reflect gene expression chan...
ORGANISM(S): Mus musculus 
2014-09-17 | E-GEOD-56249 | biostudies-arrayexpress
TranscriptomicsPrefrontal cortex gene expression in WSP and WSR male and female mice following 72h of chronic ethanol vapor exposure
Ethanol is the most common substance of abuse in the US, and abuse can lead to physical dependence, addiction, brain damage and premature death. The cycle of alcohol addiction has been described as a composite consisting of three stages: intoxication, withdrawal and craving/abstinence. As a comple...
ORGANISM(S): Mus musculus 
2014-09-17 | E-GEOD-56247 | biostudies-arrayexpress
TranscriptomicsMeDIP-chip of adult mouse hippocampus exposed to neonatal ethanol
In this experiment, we exposed mice to ethanol injections on postnatal days 4 and 7. We then extracted whole-hippocampus on postnatal day 70. We performed MeDIP-chip using an antibody against 5mC. We also perfomed MEDME anaylsis using a chip with fully methylated DNA to act as a control. We found a...
ORGANISM(S): Mus musculus 
2015-07-25 | E-GEOD-71313 | biostudies-arrayexpress
ProteomicsA proteomic analysis of WASH complex subunit 3 deficiency in adult heart.
The WASH complex is primarily responsible for the activation of actin branching on endosomes, regulating vesicle trafficking across intracellular organelles. As one of the core subunits of the WASH complex, the function of washc3 remains largely unknown. In this study, we performed proteomic analysi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-03-09 | PXD062550 | Pride
Heart Mitochondria Wash3 Zebrafish Proteomics 
TranscriptomicsTranscriptomic analysis of two ethanol-tolerant Saccharomyces cerevisiae clones obtained by evolutionary engineering
Evolutionary engineering strategy was used for selection of ethanol-tolerant Saccharomyces cerevisiae clones under gradually increasing ethanol stress levels. Clones B2 and B8 were selected based on their higher ethanol-tolerance and higher ethanol production levels. Whole genome microarray analysis...
ORGANISM(S): Saccharomyces cerevisiae 
2016-03-01 | E-GEOD-78759 | biostudies-arrayexpress
UnknownYeast Derived LysA2 Can Control Bacterial Contamination in Ethanol Fermentation.
Not available
S-EPMC6024572 | biostudies-literature
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