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ProteomicsA proteomic analysis of WASH complex subunit 3 deficiency in adult heart.
The WASH complex is primarily responsible for the activation of actin branching on endosomes, regulating vesicle trafficking across intracellular organelles. As one of the core subunits of the WASH complex, the function of washc3 remains largely unknown. In this study, we performed proteomic analysi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-03-09 | PXD062550 | Pride
Heart Mitochondria Wash3 Zebrafish Proteomics 
ProteomicsTENT5 cytoplasmic non-canonical poly(A) polymerases regulate the innate immune response in animals
Innate immunity, the first line of host defense against pathogens, is tightly regulated both transcriptionally and post-transcriptionally. Here, through global transcriptome and proteome analyses in Caenorhabditis elegans, we uncover a modulation of the expression of secreted innate immunity effecto...
ORGANISM(S): Caenorhabditis elegans 
2022-05-31 | PXD023238 | Pride
Innate immunity Cytoplasmic polyadenylation Non-canonical polyadenylation Tent5 Direct rna sequencing Terminal nucleotidyltransferase C. elegans innate immunity 
ProteomicsProteomics of serum extracellular vesicles from patients with advanced melanoma treated with anti-PD1 inhibitors
Protein content of extracellular vesicles from serun of advanced melanoma patients treated with anti-PD1 therapy.
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD062378 | Pride
Pd1 Extracellular vesicles Melanoma 
ProteomicsPersonalized Molecular Signatures of Insulin Resistance and Type 2 diabetes
Insulin resistance is a hallmark of type 2 diabetes, a highly heterogeneous condition with diverse pathological characteristics. Understanding the molecular adaptation to insulin resistance and its association with individual phenotypic traits is crucial for advancing precision medicine in diabetes....
ORGANISM(S): Homo sapiens (Human) 
2025-05-27 | PXD049129 | Pride
Phosphoproteomics Signaling Human skeletal muscle 
TranscriptomicsTranscription profiling of Streptococcus pyongenes wild type GAS M1 strain compared to perR deletion mutant in mid and late log growth phases
Analysis of PerR regulon. Global transcription profile of wild type GAS M1 (SF370) as compared to perR deletion mutant in mid- and late- log growth phases
ORGANISM(S): Streptococcus pyogenes 
2009-01-01 | E-MEXP-1625 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptococcus agalactiae wild type and delta covRS strains at different pH conditions
Analysis of CsrRS (CovRS) two-component system. Global transcription profile of wild type GBS 2603V/R and covRS deletion mutant strains at neutral and acidic pH conditions
ORGANISM(S): Streptococcus agalactiae 
2010-05-13 | E-TABM-708 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of wt and PerR mutant Group A streptococcus (GAS), strain 003Sm in THB medium, with and without hydrogen peroxide
Transcriptome analysis of of wt and PerR mutant Group A streptococcus strain 003Sm grown in the presence or absence of hydrogen peroxide, at early and late log
ORGANISM(S): Streptococcus pyogenes 
2011-11-18 | E-MTAB-646 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of wt and PerR mutant Group A streptococcus (GAS), strain 003Sm in THB medium, with and without hydrogen peroxide
Transcriptome analysis of of wt and PerR mutant Group A streptococcus strain 003Sm grown in the presence or absence of hydrogen peroxide, at early and late log
ORGANISM(S): Group A streptococcus 
2011-12-31 | E-MTAB-628 | biostudies-arrayexpress
TranscriptomicsmiRNA chronic OVA aerosol
specific pathogen-free female BALB/c mice aged 7-8 weeks (Animal Resources Centre, Perth, Western Australia) were systemically sensitised by intraperitoneal injection of 50 M-5g of alum-precipitated chicken egg OVA (Grade V, ?98% pure, Sigma Australia) 21 and 7 days before inhalational challenge, th...
ORGANISM(S): Mus musculus 
2011-06-10 | E-MEXP-3118 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of the MSL-1 and MSL-3 vs a mock IP in Drosophila and transcription profiling of X linked genes in WT male or female III instar larvae to provide X chromosome wide profiling of MSL-1 distribution and dosage compensation in Drosophila
Dosage compensation ensures that males and females, despite unequal number of X chromosomes, equalize for X linked gene expression. In Drosophila, it is achieved by a two-fold up-regulation of most of the genes present on the male X chromosome, and requires the association of the Dosage Compensation...
ORGANISM(S): Drosophila melanogaster 
2006-04-01 | E-MEXP-554 | biostudies-arrayexpress
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