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PI: Experiments and fish exposures were performed in the laboratory of Frederic Silvestre at the University of Namur (Belgium). Proteomics contact: Proteomics sample preparation and biological mass spectrometry were performed in the laboratory of Prof. Dietmar Kueltz at UC Davis (CA). LC-MS/MS data ...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082814 | MassIVE
LC-MS/MS data obtained from gonads of 17 adult mangrove rivulus exposed to different doses of 17-alpha-ethinylestradiol during early development. All fish acclimations, treatments, experimental design, and data anlyses were performed in Frederic Silvestre's laboratory at the University of Namur, Bel...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082816 | MassIVE
LC-MS/MS data obtained from livers of 17 adult mangrove rivulus exposed to different doses of 17-alpha-ethinylestradiol during early development. All fish acclimations, treatments, experimental design, and data anlyses were performed in Frederic Silvestre's laboratory at the University of Namur, Bel...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082815 | MassIVE
Male rat treated with 17-alpha-Ethinylestradiol for 24 hours. Hepatic gene expression changes in comparison with control, excepient treated rats.
ORGANISM(S): Rattus norvegicus 
To understand the contribution of direct versus indirect DNA binding of estrogen-activated ERa and ERa(EAAE/EAAE) on gene expression in the murine liver, RNA was isolated from the liver of wild-type and ERa(EAAE/EAAE) mice treated perorally with 100µg/kg ethinylestradiol(EE) or vehicle for 4 or 24 h...
ORGANISM(S): Mus musculus 
The goal of this study is to characterize molecular toxicity pathways associated with ethinylestradiol-induced toxicity and link these molecular perturbations to apical outcomes of regulatory relevance.
ORGANISM(S): Pimephales promelas 
2021-04-09 | PXD021155 | Pride
Ethinylestradiol (EE)-based combined oral contraceptives (COC) have multiple beneficial effects besides contraception, but they also cause certain unfavorable health outcomes. They interfere, for example, with metabolism, inflammation, hepatic protein synthesis, and blood coagulation. COCs containin...
ORGANISM(S): Homo sapiens (Human) 
2022-11-25 | PXD033618 | Pride
Ethinylestradiol (EE)-based combined oral contraceptives (COC) have multiple beneficial effects besides contraception, but they also cause certain unfavorable health outcomes. They interfere, for example, with metabolism, inflammation, hepatic protein synthesis, and blood coagulation. COCs containin...
ORGANISM(S): Homo sapiens (Human) 
2022-11-25 | PXD033617 | Pride
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio 
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