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TranscriptomicsGenome wide methylation profliling of ETMR tumours.
Genome wide DNA methylation profiling of normal, ETMR and PNET tumours Bisulphite converted DNA from 12 ETMR, 28 PNET and 34 control samples hybridised to the Illumina 450k Human Methylation Beadchip Please note that three of the 12 EMTR samples are tumor, cell line and xenograft sample derived from...
ORGANISM(S): Homo sapiens 
2013-11-21 | E-GEOD-52556 | biostudies-arrayexpress
ProteomicsIntegrated proteomics spotlight the proteasome as a pervasive therapeutic vulnerability in Embryonal Tumors with Multilayered Rosettes (ETMR)
Embryonal tumors with multilayered rosettes (ETMR) are rare malignant embryonal brain tumors. The prognosis of ETMR is poor and novel therapeutic approaches are desperately needed. Comprehension of ETMR tumor biology is based on only few previous molecular studies, which mainly relied on the analyse...
ORGANISM(S): Homo sapiens (Human) 
2024-01-08 | PXD045268 | Pride
Transcriptome Multiomics Embryonal tumor with multilayered rosettes Mass spectrometry 850k Methylome Etmr Embryonal brain tumor Lin28a Dna methylation Proteome 
TranscriptomicsGene expression data from ETMR cell line BT183
Gene expression data from this ETMR cell line was compared with gene expression data from primary ETMR tumors to search for potential drug targets in ETMR tumors.
ORGANISM(S): Homo sapiens 
2020-02-15 | GSE94985 | GEO
GenomicsETMR stem-like state and chemoresistance are supported by perivascular cells at single-cell resolution
ETMR stem-like state and chemoresistance are supported by perivascular cells at single-cell resolution
PRJNA1072016 | ENA
GenomicsCellular hierarchies of ETMR are shaped by oncogenic miRNAs and receptor-ligand interactions
Cellular hierarchies of ETMR are shaped by oncogenic miRNAs and receptor-ligand interactions
PRJNA967009 | ENA
UnknownETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution.
Not available
S-EPMC12198369 | biostudies-literature
UnknownLCLAT1 regulates cardiolipin composition, mitochondrial phenotype, Lin28A, and oncogenic signaling networks in ETMR.
Not available
S-EPMC12746605 | biostudies-literature
GenomicsETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (murine subset)
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (murine subset)
PRJNA934566 | ENA
TranscriptomicsETMR stem-like state and chemoresistance are supported by perivascular cells at single-cell resolution
To investigate the cellular heterogeneity of ETMR and the role of pericytes in the tumor microenvironment, we performed sequencing at single-cell resolution of about 250,000 cells from primary human and murine ETMR as well as from 2D ETMR cultures and 3D models of ETMR-harboring forebrain organoids....
ORGANISM(S): Homo sapiens 
2025-04-17 | GSE254819 | GEO
GenomicsETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (human subset)
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (human subset)
PRJNA934567 | ENA
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