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ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology of Thalidomide
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery, enabling new therapeutic paradigms unprecedented with other drug classes such as catalytic enzyme inhibitors. Immunomodulatory or PROTAC drugs are a prime example for proximity-...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD041097 | Pride
Eubopen crbn thalidomide 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology of Iberdomide
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery, enabling new therapeutic paradigms unprecedented with other drug classes such as catalytic enzyme inhibitors. Immunomodulatory or PROTAC drugs are a prime example for proximity-...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD041081 | Pride
Eubopen crbn iberdomide 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology of Lenalidomde
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery, enabling new therapeutic paradigms unprecedented with other drug classes such as catalytic enzyme inhibitors. Immunomodulatory or PROTAC drugs are a prime example for proximity-...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD041200 | Pride
Eubopen crbn lenalidomide 
ProteomicsChemBioID - An integrated chemical biology workflow for the analysis of inhibitor induced USP21 target proximity
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery, enabling new therapeutic paradigms unprecedented with other drug classes such as catalytic enzyme inhibitors. Immunomodulatory or PROTAC drugs are a prime example for proximity-...
ORGANISM(S): Homo sapiens (Human) 
2023-04-25 | PXD041068 | Pride
Usp21 Eubopen Bioid 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology of CC-885
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery, enabling new therapeutic paradigms unprecedented with other drug classes such as catalytic enzyme inhibitors. Immunomodulatory or PROTAC drugs are a prime example for proximity-...
ORGANISM(S): Homo sapiens (Human) 
2023-04-26 | PXD041128 | Pride
Eubopen crbn cc-885 
UnknownEUbOPEN chemotranscriptomics dose-response + IC50
Not available
ORGANISM(S): Homo sapiens (human) 
S-BSST2203 | biostudies-other
UnknownSynthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities.
Not available
S-EPMC10707894 | biostudies-literature
UnknownThe ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods.
Not available
S-EPMC10767899 | biostudies-literature
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery. Here we probe the effects of catalytic inhibition on the proximity of CAMKK2. The experiment was supervised by Sabrina Keller and Viviane Reber. This project is part of the IMI ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD058418 | Pride
Bioid 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery. Here we probe the effects of catalytic inhibition on the proximity of CAMKK2. The experiment was supervised by Sabrina Keller and Viviane Reber. This project is part of the IMI ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD058412 | Pride
Bioid 
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