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ProteomicsAmplified fluorogenic immunoassay for early diagnosis and monitoring of Alzheimer’s disease from tear fluid
Accurate diagnosis of Alzheimer’s disease (AD) in its earliest stage can prevent the disease and delay the onset of symptoms by maintaining a healthy lifestyle and controlling modifiable risk factors. Therefore, more sensitive, relatively inexpensive, non-invasive, and simple screening tools are req...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042142 | Pride
Alzheimer’s disease Immunoassay Magnetic nanoparticles Polymeric nanoprobes Tear fluid 
ProteomicsSynphilin-1 upregulates RBL2 expression and causes a G0/G1 phase cell cycle arrest in the neurons
Synphilin-1, a major component of Lewy bodies in the brain of Parkinsons disease (PD) patients, is a cytoplasmic protein that interacts with alpha-synuclein and is suggested to have cytoprotective effects in the neuronal cells. alpha-Synuclein overexpression induced re-entry of the neuronal cells in...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2022-07-20 | MSV000089926 | MassIVE
ProteomicsIdentification of Missing Proteins in Human Olfactory Epithelial Tissue by Liquid Chromatography-Tandem Mass Spectrometry
We performed proteomic analyses of human olfactory epithelial tissue to identify missing proteins using liquid chromatography-tandem mass spectrometry. Using a next-generation proteomic pipeline with a <1.0% false discovery rate at the peptide and protein levels, we identified 3,731 proteins, among ...
ORGANISM(S): Homo sapiens (Human) 
2018-08-17 | PXD010025 | Pride
Human Olfactory epithelial tissue Missing protein Lc-ms/ms 
UnknownT-cell-restricted intracellular antigen 1 facilitates mitochondrial fragmentation by enhancing the expression of mitochondrial fission factor.
Not available
S-EPMC5260506 | biostudies-literature
ProteomicsRetinal proteome analysis reveals region-specific change in the rabbit myopia model
Uncovering region-specific change in myopic retina can provide the clue for explaining the pathogenesis of myopia progression. After imposing form deprivation myopia (FDM) on the right eye of 6-week-old rabbits, we investigated the proteome profile of each retinal region (central, mid periphery, an...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2023-03-10 | PXD038552 | Pride
Retina Rabbit Myopia Lc-ms/ms 
ProteomicsProteomic Analysis of Retina-derived CD29 positive Müller Cells in a Myopia induced rabbit model
The prevalence of myopia is rapidly increasing, significantly impacting the quality of life for affected individuals. Prior research in our group observed reactive gliosis in Müller cells within myopia-induced retinas, prompting further investigation into their role in myopia. In this study, we anal...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2025-05-07 | PXD053804 | Pride
Myopia Müller cells Proteomics Oxidative stress Glycolysis 
UnknownClinical characteristics and prognostic factors of myocarditis associated with the mRNA COVID-19 vaccine.
Not available
S-EPMC9015469 | biostudies-literature
TranscriptomicsExpression of M-CSF from cryopreserved teeth-derived human periodontal ligament cells with different freezing protocols
This study investigated which genes regarding root resorption are upregulated by cryopreservation and whether cryopreservation affects the expression of Macrophage M-bM-^@M-^Scolony stimulating factor. We manufactured the customized template which was made of genes selected regarding root resorption...
ORGANISM(S): Homo sapiens 
2013-01-19 | E-GEOD-43611 | biostudies-arrayexpress
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