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Here we use HDX to study covalently modified Rab1a and RalA in both their apo states and bound to MRTX1257 to see how this compound affects the overall secondary structure of the proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD041440 | Pride
Analysis of the interactions between WDR44 and Rab11 utilizing HDX-MS
ORGANISM(S): Homo sapiens (Human) 
2023-02-22 | PXD032837 | Pride
DR44 is a Rab11 effector protein that is thought to regulate ciliogenesis by competing with pro-ciliogenesis factors for Rab11 binding. The structure of WDR44 and the molecular mechanism of its interaction with Rab11 is unknown. To explore the interactions between these two proteins multiple WDR44 c...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035741 | Pride
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