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Capture of urinary EVs with EVtrap and analysis of their phosphoproteome
ORGANISM(S): Homo sapiens (Human) 
2018-08-10 | PXD010480 | Pride
Invasive nature and pain caused to patients inhibit the routine use of tissue biopsy-based procedures for cancer diagnosis and surveillance. The analysis of extracellular vesicles (EVs) from biofluids have recently gained significant traction in the liquid biopsy field. EVs offer an essential “snaps...
ORGANISM(S): Homo sapiens (Human) 
2020-06-15 | PXD017994 | Pride
Urine extracellular vesicles from NSCLC patients were analyzed via LC-MS/MS to identify host and microbial proteins associated with progression-free survival. The study included 33 baseline urine samples and follow-up data. Samples were processed using EVtrap and analyzed on a Q-Exactive HF-X using ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-10 | PXD062630 | Pride
This pilot study aimed to characterize the proteomic and phosphoproteomic landscape of circulating EVs in participants with established T1D (N=10) and healthy normal volunteers (Controls) (N=7) (NCT03379792) carefully matched by age, race/ethnicity, sex, and BMI. EVs were isolated using EVtrap® tech...
ORGANISM(S): Homo sapiens (Human) 
2023-07-13 | PXD041899 | Pride
Primary central nervous system lymphoma(PCNSL) is a rare extra-nodal non-Hodgkin’s lymphoma and accounts for 3%-4% of central nervous system tumors. Recent studies have highlighted the importance of cerebrospinal fluid derived extracellular vesicles in PCNSL. Extracellular vesicles(EVs) are nanoscal...
ORGANISM(S): Homo Sapiens (human) 
Extracellular vesicles (EVs) have emerged as promising drug-delivery vehicles. Genetic engineering of a membrane-bound, EV-sorting scaffold protein empowers these cell-borne nanosized vesicles by installing targeting moieties on the surface and enriching therapeutic cargo in the lumen. However, the ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD057965 | Pride
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