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ProteomicsThe Angiostrongylus vasorum excretory/secretory proteome contains putative modulators of the host coagulation
Angiostrongylus vasorum is a cardiopulmonary nematode of canids and is, among others associated with bleeding disorders in dogs. The pathogenesis of coagulopathies remains unclear. We performed a deep proteomic characterization of sex specific A. vasorum excretory/secretory proteins (ESP) and of cut...
ORGANISM(S): Angiostrongylus vasorum 
2021-11-03 | PXD027520 | Pride
Angiostrongylus vasorum Excretory/secretory Cuticular surface 
ProteomicsOpisthorchis felineus excretory-secretory product (ESP) and lysate proteomics by GeLC-MS / MS
A significant number of pathological conditions, accompanied by chronic non-healing wounds, demands searching for new modern therapeutic approaches. Well-documented ability of O. felineus to initiate extracellular matrix (ECM) remodeling and liver epithelium regeneration suggests that its bioactive ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD037991 | Pride
Opisthorchis felineus Sds-page Excretory-secretory product Lysate Lc-ms/ms 
ProteomicsClonorchis sinensis-Excretory/Secretory Proteins ameliorates Inflammation in Rheumatoid Arthritis and Ankylosing Spondylitis
We aimed to investigate whether substances secreted by Clonorchis sinensis-Excretory/Secretory protein (CS-ESP), rather than direct contact with crude proteins, have an effect on the inflammation of rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and to identify specific peptides through ...
ORGANISM(S): Clonorchis sinensis 
2025-05-07 | PXD059467 | Pride
Lc-msms Clonorchis sinensis Excretory/secretory protein (esp) 
ProteomicsN-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade
The cardiopulmonary nematode Angiostrongylus vasorum can cause severe disease in dogs, including coagulopathies manifesting with bleeding. We analysed A. vasorum excretory/secretory protein (ESP)-treated dog plasma and serum by N-terminome analysis using Terminal Amine Isotopic Labelling of Substrat...
ORGANISM(S): Angiostrongylus vasorum Canis familiaris (Dog) (Canis lupus familiaris) 
2025-05-07 | PXD056659 | Pride
Dog Serum French heartworm Plasma Tails 
ProteomicsQualitative and Quantitative proteomic analyses of Schistosoma japonicum Eggs and Egg-derived Secretory-Excretory proteins
Schistosome parasites lay up to a thousand eggs per day inside the veins of their mammalian hosts. The immature eggs deposited by females against endothelia of venules will embryonate within days. Approximately 30% of the eggs will migrate to the lumen of the intestine to continue the parasite lif...
ORGANISM(S): Candida albicans (Yeast) 
2019-09-26 | PXD012835 | Pride
Schistosoma japonicum Swath analysis. Mass spectrometry Schistosomiasis Esp Eggs 
UnknownCanine Brugia malayi microfilarial excretory/secretory protein-based antibody assay for the diagnosis of brugian filariasis in dogs.
Not available
S-EPMC6841868 | biostudies-literature
ProteomicsEvidence of immune modulators in the secretome of the equine tapeworm Anoplocephala perfoliata
Anoplocephala perfoliata is a neglected gastro-intestinal tapeworm, commonly infecting horses worldwide. Molecular investigation of A. perfoliata is hampered by a lack of tools to better un-derstand the host-parasite interface. This interface is likely influenced by parasite derived immune modulator...
ORGANISM(S): Anoplocephala perfoliata 
2021-07-26 | PXD027105 | Pride
Anoplocephala perfoliata  secretome  extracellular vesicles  ev surface  ev depleted esp  lcmsms 
ProteomicsComparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites
Filarial nematodes (superfamily Filarioidea) are responsible for an annual global health burden of approximately 6.3 million disability-adjusted life-years, which represents the greatest single component of morbidity attributable to helminths affecting humans. No vaccine exists for the major filaria...
ORGANISM(S): Litomosoides sigmodontis (Filarial nematode worm) 
2014-07-22 | PXD000756 | Pride
Filarial nematode Excretory-secretory products Lc-ms/ms Litomosoides sigmodontis 
UnknownThe Angiostrongylus vasorum Excretory/Secretory and Surface Proteome Contains Putative Modulators of the Host Coagulation.
Not available
S-EPMC8593241 | biostudies-literature
UnknownProteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information.
Not available
S-EPMC3201918 | biostudies-literature
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