Sort   by:  
 Page size 
TranscriptomicsNuclear Matrix Association in Proliferative and Invasive Cytotrophoblasts
Abnormal trophoblast invasion is associated with the most common and most severe complications of human pregnancy. The biology of invasion, as well as the etiology of abnormal invasion remains poorly understood. The aim of this study was to characterize the transcriptome of the HTR-8/SVneo human c...
ORGANISM(S): Homo sapiens 
2010-06-22 | E-GEOD-17501 | biostudies-arrayexpress
TranscriptomicsMolecular prediction of gastrulation stages with small extra-embryonic gene-set
Axis specification in mouse is determined by a sequence of reciprocal interactions between embryonic and extra-embryonic tissues so that a few extra-embryonic genes appear as ‘patterning’ the embryo. Considering these interactions as essential, but lacking in most mammals the genetically driven appr...
ORGANISM(S): Bos taurus 
2010-06-24 | E-GEOD-13013 | biostudies-arrayexpress
ProteomicsRole of mTOR in regulating the extra cellular matrix
Explored the potential role of mTOR in regulating the extra cellular matrix of TGF-b1-stimulated IPF fibroblasts grown under macromolecular crowding conditions in the presence of either CZ415 or rapamycin
ORGANISM(S): Homo sapiens (Human) 
2018-11-04 | PXD010164 | Pride
Cz415 Mtori Ipf fibroblasts 
ProteomicsEffects of PRSS35 on the extra cellular matrix
In the project four sets of label-free proteomics studies were performed to characterize the extra cellular matrix (ECM) proteome of differentially treated cells (see below). All cells were treated with sorbitol to induce the expression of PRSS35. Only in set IV PRSS35 is downregulated. For each set...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD040684 | Pride
Human Ecm Lc-msms Skin Fibroblast 
GenomicsA long-term feeder-free culture method for human pancreatic progenitors on extra cellular matrix or matrix-free polymers
A long-term feeder-free culture method for human pancreatic progenitors on extra cellular matrix or matrix-free polymers
PRJEB42423 | ENA
TranscriptomicsMatrix Elasticity Does Not Affect Replicative Senescence or DNA Methylation Patterns of Mesenchymal Stem Cells [gene expression profiling]
Matrix elasticity influences differentiation of mesenchymal stem cells (MSCs) but it is unclear if these effects are only transient - while the cells reside on the substrate - or if they reflect persistent lineage commitment. In this study, MSCs were continuously culture-expanded in parallel either ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-55867 | biostudies-arrayexpress
GenomicsElevated Extra-cellular Matrix Signaling in Adipose Mesothelial Cells is Linked to Insulin Resistance in Obesity
Elevated Extra-cellular Matrix Signaling in Adipose Mesothelial Cells is Linked to Insulin Resistance in Obesity
PRJNA528456 | ENA
GenomicsExtra centrosomes delay DNA damage-driven tumorigenesis
Centrosomes act as microtubule organizing centers and are critical for faithful chromosome segregation in mitosis. Deregulated centrosome numbers are frequently found in human cancer and can promote malignancies in model organisms. Current research aims to clarify if extra centrosomes are cause or c...
ORGANISM(S): Mus musculus 
2026-01-22 | E-MTAB-13724 | biostudies-arrayexpress
ProteomicsProfiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets
Intervertebral disc degeneration is accompanied by a loss of Extra-cellular matrix (ECM) content due to an imbalance in anabolic and catabolic pathways. Identifying ECM proteins with anabolic and/or regenerative potential could be the key to developing regenerative therapies. Since human fetal discs...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD021431 | Pride
Np Esi-lc-ms/ms Adult Human Fetus Regenerative potential. Ivd Degenerated discs 
TranscriptomicsTranscription profiling of human rheumatoid arthritis patients derived synovial fibroblasts - using boolean network models for extracellular matrix formation
Background ; Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by joint destruction and perpetuated by the synovial membrane (SM). In the inflamed SM, activated synovial fibroblasts (SFB) form the major cell type promoting development and progression of the disease by an abn...
ORGANISM(S): Homo sapiens 
2009-08-07 | E-GEOD-13837 | biostudies-arrayexpress
Sort   by:  
 Page size