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FYCO1 (FYVE and coiled-coil domain containing 1) is an adaptor protein, expressed ubiquitously and required for microtubule-dependent, plus-end-directed transport of macroautophagic/autophagic vesicles. We have previously shown that loss-of-function mutations in FYCO1 cause cataracts wit...

2024-03-24 | MTBLS206 | MetaboLights
Exosomes and microvesicles (i.e., extracellular vesicles; EVs) have been identified within ovarian follicular fluid, and recent evidence suggests that EVs are able to elicit profound effects on ovarian cell function. While existence of miRNA within EVs has been reported, it remains unknown if EV si...
ORGANISM(S): Bos taurus 
Bacterial extracellular vesicles (BEVs) produced by members of the intestinal microbiota can contribute not only to digestion but also mediate microbe-host cell communication via the transfer of functional biomolecules to mammalian host cells. An unresolved question is what host factors and conditio...
ORGANISM(S): Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) Mus musculus (Mouse) 
2025-05-26 | PXD062737 | Pride
Extracellular vesicles play a pivotal role in the intercellular communications influencing various physiological and pathological processes. They carry a range of biomolecular cargoes including small non-coding RNAs which could serve as potential diagnostic biomarkers and therapeutic targets. In the...
ORGANISM(S): Homo sapiens 
2023-03-30 | GSE216355 | GEO
Two sets of extracellular vesicles (EVs) are presented here. The first set was isolated from the supernate of cell lines. Vector control and Stard11 knock outs. Treatment with and without palmitate was done to the two groups. In total 4 study groups each containing n=3 samples. The second set o...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2021-08-27 | MSV000088031 | MassIVE
While of growing interest in pancreatic cancer (PC) field, the stromal-tumor cells crosstalk lags behind in terms of biomarkers and therapeutic options improving the clinical armamentarium. Knowledge on cellular communications was drastically enhanced following the discovery of extracellular vesicle...
ORGANISM(S): Homo sapiens (Human) 
2022-08-21 | PXD023165 | Pride
Small non-coding RNA’s profile of sorted plasma extracellular vesicles expressing different cell origin
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