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MetabolomicsBifidobacterium bifidum-derived nanoparticles attenuate alcoholic liver disease via enhanced hepatic phagocytosis and gastrointestinal homeostasis
Alcohol-associated liver disease (ALD) has limited therapeutic options due to its complex pathogenesis. This study demonstrates the ALD-protective effects of extracellular nanoparticles derived from Bifidobacterium bifidum (BNPs), focusing on the novel concept of gut microbiota-derived nanoparticles...
2025-06-19 | MTBLS12612 | MetaboLights
TranscriptomicsComparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles containing specific repertoires of genetic material. In mammals, EVs can mediate the horizontal transfer of various cargos and signaling molecules, notably miRNA and mRNA species. Whether this form of intercellular communication prevai...
ORGANISM(S): Homo sapiens 
2016-06-15 | E-GEOD-76173 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of BEAS-2B cells treated with low doses of Ni and NiO nanoparticles as well as NiCl2 for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (0.5 µg/mL) of Ni and NiO nanoparticles and NiCl2. At the end of the exposure control and treated samples were submitted for RNA-Seq analysis (Hiseq2500). The overall goal of this experiment was to gain an in-depth understa...
ORGANISM(S): Homo sapiens 
2020-04-19 | E-MTAB-8903 | biostudies-arrayexpress
ProteomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Advances in understanding intercellular communication through extracellular vesicles (EVs) and non-vesicular extracellular nanoparticles (NVEPs) have been limited by their cellular heterogeneity and unclear origins. Using sequential ultracentrifugation, we identified high- and low-density EVs and pe...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD059671 | Pride
Supermeres Extracellular nanoparticles Exomeres Extracellular vesicles Glioblastoma Egfr 
ProteomicsFast and robust proteome screening platform identifies neutrophil extracellular trap formation in the lung in response to cobalt ferrite nanoparticles
The goal of this study was to investigate the effects of magnetic iron cobalt oxide nanoparticles (cobalt doped Fe3O4 nanoparticles with increasing amounts of cobalt) after pulmonary exposure while in parallel presenting a proteomics platform that is easily transferable to large-scale nanotoxicology...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-26 | PXD016148 | Pride
Tmt Iron cobalt oxide nanoparticles Balf Lung Clinical proteomics Nanoparticles Mouse Murine Label-free Metal oxide nanoparticles Bronchoalveolar lavage fluid 
GenomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Diversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
PRJNA1209840 | ENA
GenomicsJanus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms
Janus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms
PRJNA999229 | ENA
GenomicsBioinspired TIMP-1 Nanoparticles Mimic Extracellular Vesicle Anti-angiogenic Activity in Ewing Sarcoma
Bioinspired TIMP-1 Nanoparticles Mimic Extracellular Vesicle Anti-angiogenic Activity in Ewing Sarcoma
PRJNA1475009 | ENA
ProteomicsContracting Skeletal Muscle Releases Antioxidant-Enriched Extracellular Vesicles and Non-vesicular Extracellular Nanoparticles
This study investigated extracellular vesicles and non-vesicular extracellular nanoparticles released from C2C12 skeletal muscle myotubes following electrical pulse stimulation (EPS). Quantitative proteomics was used to characterize protein profiles and identify changes associated with EPS and antio...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD084099 | Pride
C2c12 Proteomics Electrical pulse stimulation Non-vesicular extracellular nanoparticles Extracellular vesicles Skeletal muscle Data-independent acquisition 
GenomicsTranscripitonal analysis of genes in the mouse liver that regulated by extracellular nanoparticles by Next-Generation Sequencing
Transcripitonal analysis of genes in the mouse liver that regulated by extracellular nanoparticles by Next-Generation Sequencing
PRJNA707336 | ENA
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