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ProteomicsProteome of DiFi EVs, exomeres and supermeres purified by ultracentrifugation and FPLC
The cell seretome is diverse and contains extracellular secreted vesicles (EVs) as well as non-vesicular extracellular nanoparticles (NVEPs) called exomeres and supermeres, all of which carry different kinds of cell signaling cargos. We have developed new techniques to purify exomeres and supermeres...
ORGANISM(S): Homo sapiens (Human) 
2025-09-11 | PXD066872 | Pride
Supermeres Exosomes Ultracentrifugation Fplc Proteomics Exomeres Extracellular vesicles 
UnknownTransfer of Functional Cargo in Exomeres.
Not available
S-EPMC6559347 | biostudies-literature
UnknownExomeres and Supermeres: monolithic or diverse?
Not available
S-EPMC9610496 | biostudies-literature
UnknownA scalable filtration-based method for isolating exomeres and other nanoscale extracellular particles.
Not available
S-EPMC12633226 | biostudies-literature
UnknownMultiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism.
Not available
S-EPMC7539214 | biostudies-literature
ProteomicsSupermeres in breast and pancreatic cancer cells
Extracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses o...
ORGANISM(S): Homo sapiens (Human) 
2021-12-01 | PXD027258 | Pride
Proteomics Supermere Sevs Exomere Cancer 
UnknownExomeres From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promote Vascular Remodelling via Transferring Osteopontin.
Not available
S-EPMC12326188 | biostudies-literature
ProteomicsSupermeres, a new functional extracellular nanoparticle replete with disease biomarkers and therapeutic target
Extracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses o...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD025213 | Pride
Human Sev Supermere Exomere Difi Colorectal cancer Lc-ms/ms 
ProteomicsMultiresolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism
Extracellular particles (EPs) including extracellular vesicles and exomeres play a significant role in diseases and therapeutic applications. However, the spatiotemporal dynamics of EPs in vivo remains to be elucidated with a suitable method. In this study, we developed a bioluminescence resonance e...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020446 | Pride
Extracellular vesicles Hepatocellular carcinoma Microvesicles Exosomes Biodistribution Redirected tropism 
TranscriptomicsTranscripitonal analysis of genes in the mouse liver that regulated by extracellular nanoparticles by Next-Generation Sequencing
We examined the effects on the liver following systemic delivery of extracellular nanoparticles exomeres and supermeres. Mice were injected with supermeres or exomeres via tail vein.To discern possible differences in the effects of supermeres and exomeres, we performed RNA-seq analysis of the liver ...
ORGANISM(S): Mus musculus 
2021-10-12 | GSE168417 | GEO
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