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A comprehensive analysis of supermere, exomere, and extracellular vesicle isolation and cargo in colorectal cancer
Biofluids contain a heterogeneous mixture of extracellular vesicles and non-vesicular nanoparticles (including exomeres and supermeres) that transport a diverse array of proteins, RNA, and lipids. Our previous efforts to characterize the contents of these carriers in colorectal cancer relied on 2D c...
ORGANISM(S): Homo sapiens 
2025-12-04 | GSE304273 | GEO
The cell seretome is diverse and contains extracellular secreted vesicles (EVs) as well as non-vesicular extracellular nanoparticles (NVEPs) called exomeres and supermeres, all of which carry different kinds of cell signaling cargos. One supermere enriched cargo is transforming growth factor beta in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-11 | PXD066888 | Pride
Extracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses o...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD025213 | Pride
Extracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses o...
ORGANISM(S): Homo sapiens (Human) 
2021-12-01 | PXD027258 | Pride
The cell seretome is diverse and contains extracellular secreted vesicles (EVs) as well as non-vesicular extracellular nanoparticles (NVEPs) called exomeres and supermeres, all of which carry different kinds of cell signaling cargos. We have developed new techniques to purify exomeres and supermeres...
ORGANISM(S): Homo sapiens (Human) 
2025-09-11 | PXD066872 | Pride
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