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ProteomicsComparative proteomic analysis identifies specific signature proteins in small extracellular vesicles from granulocytes and CD4+ T cell subpopulations
Proteomic analysis of small extracellular vesicles (sEV) is a powerful tool for the characterization of cell-to-cell signalling. While several studies describe the proteome profile of different immune cell types, none have analysed the content of their delivered sEV. The aim of the present study was...
ORGANISM(S): Homo sapiens (Human) 
2025-02-18 | PXD046108 | Pride
Th17 Exosomes Th2 Th1 Proteomics Eosinophils Sev Neutrophils 
TranscriptomicsViral and transgene-free human induced pluripotent stem (iPS) cells using non-integrating Sendai virus (SeV) vectors.
Whole-genome expression analysis of non-integrating Sendai virus (SeV) vector and retroviral vector-generated human iPS cells. Parental fibroblast and induced pluripotent stem (iPS) cells.
ORGANISM(S): Homo sapiens 
2010-09-22 | E-GEOD-24240 | biostudies-arrayexpress
ProteomicsAkkermansia muciniphila SEV-containing proteins smaller than 30 kDa
Histone lysine lactylation (Klac) is a new posttranslational modification (PTM) that is installed by acetyltransferase to modulate specific immune responses1 and oncogenesis2,3. Akkermansia muciniphila (A. muciniphila) is a beneficial bacterium that blunts ulcerative colitis (UC) in a mouse model by...
ORGANISM(S): Akkermansia muciniphila 
2023-11-28 | PXD037100 | Pride
Lc/msms Akkermansia muciniphila Sev 
Proteomicslung cancer sEV uptake by T cells
Despite advances in immunotherapy, non-small cell lung carcinoma (NSCLC)’s clinical success is limited, possibly due to substantial immunological alterations in advanced cancer patients. This study examines the immunomodulatory effects of sEVs derived from lung adenocarcinoma (ADC) and squamous cell...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD063051 | Pride
Lung cancer Exosome Uptake Cross-treatment 
TranscriptomicsAirway Epithelial Cell Response to Sendai virus infection
Oligonucleotide microarrays were used to establish a profile for gene expression in wild-type airway epithelial cells after paramyxoviral infection. Analysis was performed on mRNA isolated from SeV-infected primary-culture mouse tracheal epithelial cells that were maintained under physiologic condit...
ORGANISM(S): Mus musculus 
2009-04-25 | E-GEOD-10211 | biostudies-arrayexpress
GenomicsmiRNA profiling of OA-UVR-sEV and corresponding Non-sEV fractions from UVR-stimulated Odorrana andersonii skin secretions
miRNA profiling of OA-UVR-sEV and corresponding Non-sEV fractions from UVR-stimulated Odorrana andersonii skin secretions
PRJNA1512757 | ENA
TranscriptomicsTranscription profiling of mouse macrophage response to sendai virus infection.
Thus, mouse macrophage cultures were established from PBMCs isolated from wild-type control mice and were inoculated with SeV (Sendai virus) or UV-SeV (UV-inactivated SeV). These microarrays were performed in concert with assays of CCL5 and CCR5 expression, viral replication, and cellular apoptosis....
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2935 | biostudies-arrayexpress
ProteomicsSmall Extracellular Vesicles Derived from Human Trabecular Meshwork Stem Cells are distinct from TM Cells in their Proteome Cargo and Function
Glaucoma is an optic neuropathy, the second leading cause of irreversible blindness worldwide. In our earlier studies, we demonstrated the isolation and functional efficacy (wound healing and anti-oxidant potential) of small extracellular vesicles (sEV) from the adult tissue-resident stem cells of t...
ORGANISM(S): Homo sapiens (Human) 
2025-06-13 | PXD059934 | Pride
Proteomics Glaucoma Small extracellular vesicles Trabecular meshwork stem cells 
TranscriptomicsGene expression profiling of mature dendritic cells from mice s. c. treated with GM-CSF-gene transduced LLC cells (LLC/SeV/GM) or control cells (LLC, LLC/SeV/GFP)
Irradiated granulocyte macrophage-colony stimulating factor (GM-CSF)-transduced autologous tumor cells induce substantial antitumor immunity through the maturation and migration of dendritic cells (DCs). However, little is known about the key molecules involved in GM-CSF-sensitized DCs (GM-DCs) in t...
ORGANISM(S): Mus musculus 
2013-09-30 | E-GEOD-43169 | biostudies-arrayexpress
TranscriptomicsTranscriptome characterization of venous endothelium during the formation of neointimal hyperplasia and stenosis in a rat arteriovenous fistula model for kidney dialysis
In patients with severe kidney disease AVF are surgically placed in order to create good access for hemodialysis. In these dialysis patients the failure rates of AVF can be as high as 24% within 6 months after surgery, causing ineffective dialysis and necessitating additional clinical interventions....
ORGANISM(S): Rattus norvegicus 
2013-10-01 | E-GEOD-46126 | biostudies-arrayexpress
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