Sort   by:  
 Page size 
MetabolomicsPrevention of acute graft-versus-host disease via single-dose administration of bioengineered extracellular vesicles
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for various hematological and immunologic diseases, but acute graft-versus-host disease (aGVHD) remains a major cause of morbidity and mortality. We previously discovered in patients and murine models that higher le...
2026-09-11 | MTBLS15633 | MetaboLights
ProteomicsTheileria annulata infectied bos taurus extracellular vesicles LC-MSMS
Extracellular vesicles (EVs) are key mediators of intercellular communication, and often play critical roles in host-parasite interactions by facilitating parasite’s physiology and pathogenesis. Theileria annulata, an apicomplexan parasite, induces profound changes in host cells, leading to uncontro...
ORGANISM(S): Bos taurus (Bovine) Theileria annulata 
2025-09-29 | PXD056906 | Pride
Dendritic cells Bos taurus B cells Serum Theileria annulata Pbmc Lc-msms 
ProteomicsMice bone marrow-derived dendritic cells (BMDC) infected by Listeria: extracellular vesicles (EVs) proteome and PTMs
In this study, we aimed to determine the role of EVs derived from Lm-infected DCs in the innate response, and the potential role of HDAC6 in DEV loading under these conditions. Our results show that Lm infection induced an elevated production of DEVs. Lm infection also altered protein sorting. Inter...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-30 | PXD033998 | Pride
Multiplexed quantitative proteomics Ubiquitinilation Acetylation Extracellular vesicles from dendritic cells Hdac6-ko 
ProteomicsAmplifying Tumor Antigen Presentations from Intratumorally Entrapped Dendritic Cells.
This study aims to characterize the proteomic changes of extracellular vesicles (DEVs) released by ginseng vesicles (GEN) or IGNITE-treated mouse bone marrow-derived dendritic cells (BMDCs) using proteomics technology. DEVs were secreted by primary BMDCs . After 24-hour treatment of mouse bone marro...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-01 | PXD077386 | Pride
Dendritic cells Antigen presentation Tumor immunotherapy Extracellular vesicles 
ProteomicsHuman melanoma-derived extracellular vesicles reprogram dendritic cells potentially enabling lymph node metastases
Evolution of melanoma from a primary tumor to widespread metastasis is crucially dependent on lymphatic spread. The mechanisms regulating the initial step in metastatic dissemination via regional lymph nodes remain largely unknown. We have previously described a dysfunctional immune profile that pre...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005539 | Pride
Metastasis4 Dendritic cells2 Lymphatics3 Extracellular vesicles1 Tumor immunology5 
ProteomicsFormation of a protein corona on the surface of extracellular vesicles in blood plasma
In this study we tested whether a protein corona is formed around extracellular vesicles (EVs) in biofluids. We isolated nascent EVs of THP1 cells and platelets, and incubated them in EV-depleted platelet-free plasma from healthy subjects and patients with rheumatoid arthritis. EVs were subjected to...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020584 | Pride
Protein corona  extracellular vesicles  blood plasma  rheumatoid arthritis  mass spectrometry  aggregation 
ProteomicsCharacterization of Fasciola heptica extracellular vesicles recovered by gravity flow
Parasite-derived extracellular vesicles (EVs) are now at the forefront of helminth research, with evidence indicating that they exhibit immune modulatory activity, presenting a strong case to look at their potential as vaccine candidates. In the present study, Fasciola hepatica derived EVs (FhEVs) w...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2021-09-09 | PXD016561 | Pride
Fasciola hepatica  extracellular vesicles  excreted-secreted proteins  gravity flow 
GenomicsImmune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells
Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells
PRJNA414968 | ENA
UnknownExtracellular vesicles derived from nasopharyngeal carcinoma induce the emergence of mature regulatory dendritic cells using a galectin-9 dependent mechanism.
Not available
S-EPMC10731827 | biostudies-literature
GenomicsDendritic cells mediated by small extracellular vesicles derived from MSCs attenuated the ILC2 activity in patients with allergic rhinitis
Dendritic cells mediated by small extracellular vesicles derived from MSCs attenuated the ILC2 activity in patients with allergic rhinitis
PRJNA952546 | ENA
Sort   by:  
 Page size