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ProteomicsExtracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy
Anti-angiogenic anticancer therapies possess immune-stimulatory properties by counteracting pro-angiogenic molecular mechanisms. We report that tumor endothelial cells ubiquitously overexpress and secrete the intermediate filament protein vimentin through type III unconventional mechanisms. Extracel...
ORGANISM(S): Homo sapiens (Human) 
2022-03-29 | PXD024426 | Pride
Vegf Angiogenesis Human Vimentin Cancer Anti-angiogenic therapy 
ProteomicsLC-MS/MS data of Extracellular Vimentin
Angiotensin-converting enzyme 2 (ACE2) has been identified as a key entry receptor for SARS-CoV-2. The involvement of other cellular components that partake in viral entry appears to be likely but is not yet fully understood. Here we describe the identification of vimentin (VIM), an intermediate fil...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD027595 | Pride
Sars-cov-2 receptor Sars-cov-2 Vimentin Spike protein Attachment factor 
GenomicsVimentin regulates mitochondrial ROS production and inflammatory responses of neutrophils
Vimentin regulates mitochondrial ROS production and inflammatory responses of neutrophils
PRJNA1093051 | ENA
ProteomicsCharacterization of Early-Phase Neutrophil Extracellular Traps in Urinary Tract Infections
Neutrophils have an important role in rapid antimicrobial defenses against and resolution of urinary tract infections (UTIs). We show that a mechanism known as neutrophil extracellular trap (NET) formation is a strategy to combat pathogens in the urinary tract. Viscous aggregates that were present i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080847 | MassIVE
UnknownExtracellular Vesicles Bearing Vimentin Drive Epithelial-Mesenchymal Transition.
Not available
S-EPMC12719745 | biostudies-literature
UnknownExtracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy.
Not available
S-EPMC9126915 | biostudies-literature
UnknownA novel interaction between extracellular vimentin and fibrinogen in fibrin formation.
Not available
S-EPMC9726209 | biostudies-literature
UnknownExtracellular Vimentin as a Target Against SARS-CoV-2 Host Cell Invasion.
Not available
S-EPMC9252327 | biostudies-literature
UnknownExtracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth.
Not available
S-EPMC4501001 | biostudies-literature
UnknownExtracellular vimentin as a target against SARS-CoV-2 host cell invasion.
Not available
S-EPMC7805437 | biostudies-literature
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