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UnknownHumanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment.
Not available
S-EPMC6988867 | biostudies-literature
UnknownN(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1.
Not available
S-EPMC2788833 | biostudies-literature
TranscriptomicsSingle-cell RNA sequencing of germ-free zebrafish embryos
The present study was conducted in the frame of the EU-funded Graphene Flagship project. We previously evaluated the impact of graphene oxide (GO) on the gut microbiome in adult zebrafish by performing 16S rRNA gene sequencing in wild-type versus AhR-deficient zebrafish. Here, we performed single-c...
ORGANISM(S): Danio rerio 
2022-07-22 | E-MTAB-11984 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of lck-GFP transgenic zebrafish
The present study was conducted in the frame of the EU-funded Graphene Flagship project. The aim is to evaluate the impact of graphene oxide (GO) on the (innate) immune system using zebrafish as a model. We previously performed single-cell RNA-sequencing of germ-free zebrafish embryos exposed to GO ...
ORGANISM(S): Danio rerio 
2022-07-23 | E-MTAB-11991 | biostudies-arrayexpress
TranscriptomicsSystems biology approaches reveal low-dose effects of nanoparticles
Here, we show that systems biology approaches can uncover mechanisms underlying cellular responses to nanomaterials. Using RNA Seq, we found that cationic nanoparticles are capable of triggering down-regulation of cell cycle-related genes in primary human bronchial epithelial cells at doses that do ...
ORGANISM(S): Homo sapiens 
2015-01-17 | E-MTAB-2397 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of BEAS-2B cells exposed to low doses of Ag nanoparticles for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (1 µg/mL) of Ag nanoparticles (10 nm citrate-coated). At the end of the exposure control and treated samples were submitted for DNA methylation analysis (Illumina 450k). The overall goal of this experiment was to evaluate p...
ORGANISM(S): Homo sapiens 
2018-04-30 | E-MTAB-6331 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of BEAS-2B cells treated with low doses of Ag nanoparticles for 6 weeks
Human bronchial lung cells (BEAS-2B) were treated for 6 weeks with low doses (1 µg/mL) of Ag nanoparticles (10 nm citrate coated). At the end of the exposure control and treated samples were submitted for RNA-Seq analysis (Hiseq2500). The overall goal of this experiment was to gain an in-depth under...
ORGANISM(S): Homo sapiens 
2018-04-30 | E-MTAB-6321 | biostudies-arrayexpress
UnknownAIF and Scythe (Bat3) regulate phosphatidylserine exposure and macrophage clearance of cells undergoing Fas (APO-1)-mediated apoptosis.
Not available
S-EPMC3471829 | biostudies-literature
UnknownThree cell deaths and a funeral: macrophage clearance of cells undergoing distinct modes of cell death.
Not available
S-EPMC6368547 | biostudies-literature
UnknownEffect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab.
Not available
S-EPMC5341184 | biostudies-literature
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