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ProteomicsMUT-7 exoribonuclease activity and localisation are mediated by an ancient domain
The MUT-7 family of 3’-5’ exoribonucleases is evolutionarily conserved across the animal kingdom and plays essential roles in small RNA production in the germline. Most MUT-7 homologs carry a C-terminal domain of unknown function named MUT7 C appended to the exoribonuclease domain. Our analysis show...
ORGANISM(S): Escherichia coli Caenorhabditis elegans 
2024-10-17 | PXD048205 | Pride
Mut7-c Mut-7 Rde-2 Mut-8 Mutator complex 
TranscriptomicsGenes differentially expressed between Bmi1-overexpressing and empty vector control neural stem/progenitor cells
Neural stem/progenitor cells were isolated from the lateral ventricle wall of 4-6 week-old CD1 mice and grown as neurospheres under low density culture conditions. Test cells were transduced with bicistronic retroviral constructs for the over-expression of Bmi1 together with eGFP, and control cells ...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-70451 | biostudies-arrayexpress
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