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ProteomicsMUT-7 exoribonuclease activity and localisation are mediated by an ancient domain
The MUT-7 family of 3’-5’ exoribonucleases is evolutionarily conserved across the animal kingdom and plays essential roles in small RNA production in the germline. Most MUT-7 homologs carry a C-terminal domain of unknown function named MUT7 C appended to the exoribonuclease domain. Our analysis show...
ORGANISM(S): Escherichia coli Caenorhabditis elegans 
2024-10-17 | PXD048205 | Pride
Mut7-c Mut-7 Rde-2 Mut-8 Mutator complex 
GenomicsLactiplantibacillus plantarum subsp. plantarum strain:Mut-7
Lactiplantibacillus plantarum subsp. plantarum strain:Mut-7 Genome sequencing and assembly
PRJNA826646 | ENA
UnknownMUT-7 exoribonuclease activity and localization are mediated by an ancient domain.
Not available
S-EPMC11347159 | biostudies-literature
UnknownC. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity.
Not available
S-EPMC7946423 | biostudies-literature
UnknownRecovery of Indigenous probiotic Lactobacillus plantarum Mut-7 on healthy Indonesian adults after consumption of fermented milk containing these bacteria.
Not available
S-EPMC8292517 | biostudies-literature
GenomicsA Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans
ERI-6/7 is a negative regulator of exogenous RNAi, however the function of SOSI-1 has never previously been characterized. We noticed that expression of sosi-1 and eri-6/7 are mutually exclusive. Due to its genomic locus being nested within the eri-6 locus, we hypothesized that sosi-1 could be actin...
ORGANISM(S): Caenorhabditis elegans 
2020-05-21 | GSE145217 | GEO
TranscriptomicsTranscription profiling of human tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes
TNF time course series of HelA tet off cells cultured in presence or absence of Dox; TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of...
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-2624 | biostudies-arrayexpress
Genomics1a6f2999-fbf6-4045-85b0-f289dcdfdb67 - samples
We profiled CD45- enriched, viable cells from GBM (n = 7) and IDH-MUT (n = 7) primary samples with multi-modality single-cell sequencing of scDNAme (by reduced representation bisulfite sequencing [RRBS]) and scRNAseq (Smart-seq2).
EGAD00001009694 | EGA
TranscriptomicsTranscriptional pathway signatures for the Aurora inhibitor Danusertib
Treatment with Aurora inhibitors has been shown to induce diverse biological responses in different tumor cell lines, in part depending on their p53 status. To characterize at the transcriptional level the effects of Danusertib we analyzed by microarray different tumor cell lines, with WT or mutant ...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-24547 | biostudies-arrayexpress
UnknownClinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma.
Not available
S-EPMC2970593 | biostudies-literature
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