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ProteomicsiTRAQ-based analysis of muscle mitochondria isolated from LONP1-mKO mice
This experiment was conducted to identify the mitochondrial protein changes in the presence and absence of LONP1 in skeletal muscle. The following abstract from the submitted manuscript describes the major findings of this work.Disuse-associated loss of muscle LONP1 impairs mitochondrial quality and...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-05 | PXD029722 | Pride
Mouse Skeletal muscle 
UnknownOrganic Acid-Induced Structural Modifications Improve Melt-Stretch Properties and Mouthfeel of Plant-Based Cheese Alternatives.
Not available
S-EPMC12607658 | biostudies-literature
ProteomicsPotential Functions of Histone H3.3K56 Acetylation in Mammals
To decipher the functions of histone H3.3 acetylation at lysine 56 in mammals using a cellular system.
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD022580 | Pride
Human H3.3k56 acetylation Triple-tof 5600 
ProteomicsCoIP-MS based method to identify FNIP1 binding proteins in exercising muscle
Using muscle-specific FNIP1 (WT) and FNIP1 (S220A Tg) muscle tissues, we identified approximately 600 potential FNIP1 (WT) or FNIP1 (S220A) binding proteins in exercising muscle tissue of the corresponding mice by the CoIP-MS method, proteomic analysis showed that both FNIP1 (WT) and FNIP1 (S220A) i...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-17 | PXD046977 | Pride
Mouse Coip. Muscle 
ProteomicsHigh Fructose-Driven Epigenetic and Metabolic Reprogramming in Glomerular Podocyte
High fructose diet has been proposed as a major contributor to metabolic syndrome, which is usually accompanied with proteinuria due to glomerular podocyte injury. However, the underlying pathological mechanisms of fructose-induced podocyte injury remain elusive. In this study, we have used an iTRAQ...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-05-19 | PXD017849 | Pride
Itraq Rat High-fructose diet Podocyte injury Epigenetic mechanism. Mitochondria dysfunction Metabolic reprogramming 
ProteomicsDevelopment of functional anti-Gn nanobodies specific for SFTSV based on next generation sequencing and proteomics
Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused by novel bunyavirus (SFTSV), with a mortality rate of 6.3% ~ 30%. To date, there is no specific treatment for SFTS. Previously, our studies demonstrate that SFTSV surface glycoprotein (Glycoprotein N, Gn) is a p...
ORGANISM(S): Camelidae 
2024-01-26 | PXD032731 | Pride
Lc ms/ms Nanobody Camel 
ProteomicsClinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion
Vascular invasion is considered as the critical risk factors for tumor recurrence of hepatocellular carcinoma (HCC). To reveal the molecular mechanisms underlying macrovascular invasion (MaVI) and metastasis in HCC, we performed an iTRAQ based proteomic study to identify notably dysregulated protein...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD011846 | Pride
Hcc  macorvascular invasion  itraq  urea cycle  proteomic signature  molecular mechanisms. 
ProteomicsTurboID-based proximity labeling to identify LONP1-targeting proteins
It is documented that intracellular succinate levels are maintained and regulated by mitochondrial complexes II. In order to define the LONP1-dependent regulators of succinate content, unbiased TurboID-based proximity labeling was employed to exploit LONP1-targeting proteins. Our results showed that...
ORGANISM(S): Homo sapiens (Human) 
2023-04-08 | PXD031197 | Pride
Lonp1 Human Turboid 
MetabolomicsDistinct metabolic profiling is correlated with bisexual flowers formation resulting from exogenous ethephon induction in melon (Cucumis melo L.)

Melon (Cucumis melo L.) is an agronomically important vegetable. Most cultivars of melon are andromonoecious and bisexual flowers only emerged from the leaf axil of lateral branches. However, the regulatory mechanism contributing to the occurrence of bisexual flowers were still obscure. ...

2022-03-10 | MTBLS2993 | MetaboLights
UnknownDifferential Metabolites in Osteoarthritis: A Systematic Review and Meta-Analysis.
Not available
S-EPMC10574084 | biostudies-literature
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