Sort   by:  
 Page size 
ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31 - Interaction Proteomics of FBXO31 in HEK293T cells
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. Immunoprecipitation followed by MS (IP-MS) was performed on HA-tagged cDNA-expressed var...
ORGANISM(S): Homo sapiens (Human) 
2024-11-05 | PXD055535 | Pride
Ap-ms Fbxo31 Ip-ms Oxidative stress Ubiquitin ligase 
ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31 – CTAP discovery
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. CTAPs can arise from internal protein cleavage events during which the N-terminal fragme...
ORGANISM(S): Homo sapiens (Human) 
2024-11-05 | PXD055814 | Pride
C-terminal amide Oxidative stress Ubiquitin ligase Fbxo31 
ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31 – Expression Proteomics
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. FBXO31(D334N) is a dominant de novo mutation found among patients with cerebral palsy. T...
ORGANISM(S): Homo sapiens (Human) 
2024-11-05 | PXD055818 | Pride
Tmt Ubiquitin ligase Fbxo31 
ProteomicsC-terminal amides mark proteins for degradation via SCF/FBXO31
FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. Profiling of active cullin-RING ubiquitin E3 ligases was performed in naive or FBXO31 kno...
ORGANISM(S): Homo sapiens (Human) 
2024-11-07 | PXD055518 | Pride
Ligase Cullin Fbxo31 Ring Scf Ubiquitin E3 
OtherFBXO31-mediated Ubiquitination of OGT Maintains O-GlcNAcylation Homeostasis to Restrain Endometrial Malignancy
CRISPR screen and biochemical characterization reveal that tumor suppressor F-box only protein 31 (FBXO31) regulates O-GlcNAcylation homeostasis in EC by ubiquitinating the O-GlcNAc transferase OGT.
ORGANISM(S): Mus musculus 
2025-01-23 | GSE287788 | GEO
UnknownAberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency.
Not available
S-EPMC10917549 | biostudies-literature
UnknownC-terminal amides mark proteins for degradation via SCF-FBXO31.
Not available
S-EPMC11821526 | biostudies-literature
UnknownDegradation of FBXO31 by APC/C is regulated by AKT- and ATM-mediated phosphorylation.
Not available
S-EPMC5798317 | biostudies-literature
UnknownFBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation.
Not available
S-EPMC10786907 | biostudies-literature
UnknownF-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.
Not available
S-EPMC2722223 | biostudies-literature
Sort   by:  
 Page size