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Little is known about the global molecular changes leading to neurodegeneration and brain dysfunction in Alzheimer's disease (AD). To study the molecular cascades involved, we chose to study the transcriptomic profile of an early-onset AD model, the 5xFAD mice, at different time points (1 month, 4 m...
ORGANISM(S): Mus musculus 
TMT-based quantitative proteomic profiling of brain tissue from multiparous and nulliparous 5xFAD mice
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD064605 | Pride
Microglia are innate immune cells of the brain that perform phagocytic and inflammatory functions in disease conditions. Transcriptomic studies of acutely-isolated microglia have provided novel insights into their molecular and functional diversity in homeostatic and neurodegenerative disease states...
ORGANISM(S): Mus musculus (Mouse) 
2018-09-18 | PXD009137 | Pride
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