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ProteomicsInterfering VE-cadherin Y685 Phosphorylation inhibits development of experimental diabetic and prediabetic retinopathy
Diabetic retinopathy involves early retinal vascular barrier breakdown and pericyte loss, yet the initiating molecular events remain poorly defined. Vascular endothelial cadherin (VE-cadherin), a key regulator of endothelial integrity, is notably reduced in diabetic and prediabetic nucleoside diphos...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-07 | PXD072047 | Pride
Y685 Pericyte Ve-cadherin Ndpkb Endothelial cell Metabolic Diabetic retinopathy 
ProteomicsEarly cardiomyopathy in prediabetic NDPK-B-deficient mice is associated with remodeling of the mitochondrial O-GlcNAc proteome
Diabetic cardiomyopathy (DCM) is characterized by myocardial remodeling that may already be evident during prediabetes, yet the molecular alterations accompanying these early changes remain poorly understood. The present study examined mouse models of Nucleoside diphosphate kinase (NDPK-B)-deficient...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-21 | PXD081812 | Pride
Prediabetes  diabetes  ndpk-b  hbp  diabetic cardiomyopathy  mitochondria 
UnknownAge-related trends in lipid levels: a large-scale cross-sectional study of the general Chinese population.
Not available
S-EPMC7202729 | biostudies-literature
UnknownCombination of susceptibility gene and traditional risk factors might enhance the performance of coronary heart disease screening strategy.
Not available
S-EPMC5620315 | biostudies-literature
UnknownInvestigating aberrantly expressed microRNAs in peripheral blood mononuclear cells from patients with treatment‑resistant schizophrenia using miRNA sequencing and integrated bioinformatics.
Not available
S-EPMC7533444 | biostudies-literature
UnknownGA3 is superior to GA4 in promoting bud endodormancy release in tree peony (Paeonia suffruticosa) and their potential working mechanism.
Not available
S-EPMC8256580 | biostudies-literature
UnknownDoes single gene expression omnibus data mining analysis apply for only tumors and not mental illness? A preliminary study on bipolar disorder based on bioinformatics methodology.
Not available
S-EPMC7458177 | biostudies-literature
UnknownApplication of starch-degradation bacteria in cigar tobacco leaf fermentation: effects on starch degradation, microbial communities and metabolic pathways.
Not available
S-EPMC12319561 | biostudies-literature
UnknownEffect of Current Density on Preparation and Properties of TF/β-PbO2 in MSA Media.
Not available
S-EPMC10077529 | biostudies-literature
UnknownConstruction and Analysis of a Diagnostic Model Based on Differential Expression Genes in Patients With Major Depressive Disorder.
Not available
S-EPMC8695921 | biostudies-literature
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